Basic Information
ID: ALA667862
Type: Binding
Description: Inhibitory activity against dihydrofolate reductase (DHFR) from rat liver
Activity Charts
Bioactivity
Activity Types for Assay ALA667862
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 260.30 | 1.25 | 1.25 |
| 300.41 | 2.84 | 2.84 |
| 342.49 | 3.84 | 3.84 |
| 300.41 | 2.85 | 2.85 |
| 258.32 | 1.81 | 1.81 |
| 300.41 | 3.18 | 3.18 |
| 272.35 | 2.06 | 2.06 |
| 314.43 | 3.49 | 3.49 |
| 244.30 | 1.55 | 1.55 |
| 328.46 | 3.53 | 3.53 |
| 314.43 | 3.15 | 3.15 |
| 300.41 | 2.76 | 2.76 |
| 286.38 | 2.37 | 2.37 |
| 272.35 | 2.11 | 2.11 |
| 258.32 | 1.86 | 1.86 |
| 286.38 | 2.54 | 2.54 |
| 286.38 | 2.45 | 2.45 |
| 246.27 | 0.95 | 0.95 |
| 440.68 | 6.66 | 6.66 |
| 406.53 | 4.20 | 4.20 |
| 316.41 | 1.73 | 1.73 |
| 406.53 | 3.95 | 3.95 |
| 300.41 | 2.76 | 2.76 |
| 276.30 | 0.95 | 0.95 |
| 356.51 | 4.32 | 4.32 |
| 243.31 | 1.43 | 1.43 |
| 332.40 | 2.43 | 2.43 |
| 373.05 | 2.34 | 2.34 |
| 263.73 | 1.78 | 1.78 |
| 271.37 | 2.25 | 2.25 |
| 299.42 | 3.06 | 3.06 |
| 299.42 | 2.89 | 2.89 |
| 271.37 | 1.94 | 1.94 |
| 257.34 | 1.68 | 1.68 |
| 245.29 | 0.82 | 0.82 |
| 602.21 | 4.29 | 4.29 |
| 482.06 | 2.45 | 2.45 |
| 468.04 | 2.15 | 2.15 |
| 275.31 | 0.83 | 0.83 |
| 284.15 | 2.12 | 2.12 |
| 285.39 | 2.42 | 2.42 |