Basic Information
ID: ALA668410
Type: Binding
Description: Inhibition of the S108N mutant of dihydrofolate reductase (DHFR)
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA668410
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 248.72 | 2.52 | 2.52 |
| 270.38 | 3.17 | 3.17 |
| 228.30 | 2.18 | 2.18 |
| 293.17 | 2.63 | 2.63 |
| 502.57 | 4.42 | 4.42 |
| 426.52 | 4.70 | 4.70 |
| 454.53 | 3.63 | 3.63 |
| 283.16 | 3.18 | 3.18 |
| 440.55 | 4.95 | 4.95 |
| 412.49 | 4.39 | 4.39 |
| 468.55 | 4.02 | 4.02 |
| 440.50 | 3.24 | 3.24 |
| 396.45 | 2.84 | 2.84 |
| 214.27 | 1.87 | 1.87 |
| 244.30 | 1.88 | 1.88 |
| 368.87 | 4.15 | 4.15 |
| 290.37 | 3.54 | 3.54 |
| 350.42 | 3.21 | 3.21 |
| 364.45 | 3.25 | 3.25 |
| 398.89 | 3.99 | 3.99 |
| 283.16 | 3.18 | 3.18 |
| 248.72 | 2.52 | 2.52 |
| 234.69 | 2.27 | 2.27 |
| 270.38 | 3.43 | 3.43 |
| 286.33 | 1.80 | 1.80 |
| 200.25 | 1.62 | 1.62 |
| 220.66 | 1.96 | 1.96 |
| 338.84 | 4.14 | 4.14 |
| 320.78 | 2.46 | 2.46 |
| 416.12 | 3.79 | 3.79 |
| 426.47 | 2.85 | 2.85 |
| 186.22 | 1.31 | 1.31 |
| 338.84 | 4.14 | 4.14 |
| 320.78 | 2.46 | 2.46 |
| 234.69 | 2.27 | 2.27 |
| 220.66 | 1.96 | 1.96 |
| 366.42 | 2.83 | 2.83 |
| 453.76 | 5.04 | 5.04 |
| 419.31 | 4.76 | 4.76 |
| 258.28 | 1.60 | 1.60 |
| 304.40 | 3.48 | 3.48 |
| 336.40 | 2.82 | 2.82 |