Basic Information
ID: ALA668414
Type: Binding
Description: Inhibitory activity against triple mutant dihydrofolate reductase (C59R S108 NI164L DHFR)
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA668414
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 230.27 | 1.24 | 1.24 |
| 260.30 | 1.25 | 1.25 |
| 306.37 | 2.81 | 2.81 |
| 426.52 | 4.70 | 4.70 |
| 454.53 | 3.63 | 3.63 |
| 440.55 | 4.95 | 4.95 |
| 412.49 | 4.39 | 4.39 |
| 468.55 | 4.02 | 4.02 |
| 440.50 | 3.24 | 3.24 |
| 396.45 | 2.84 | 2.84 |
| 350.42 | 3.21 | 3.21 |
| 364.45 | 3.25 | 3.25 |
| 426.47 | 2.85 | 2.85 |
| 336.40 | 2.82 | 2.82 |
| 314.43 | 3.58 | 3.58 |
| 336.40 | 2.82 | 2.82 |
| 306.37 | 2.81 | 2.81 |
| 304.35 | 1.57 | 1.57 |
| 258.32 | 2.02 | 2.02 |
| 302.38 | 2.42 | 2.42 |
| 482.58 | 4.19 | 4.19 |
| 344.46 | 3.59 | 3.59 |
| 274.32 | 1.64 | 1.64 |
| 380.45 | 3.09 | 3.09 |
| 350.42 | 3.08 | 3.08 |
| 288.35 | 2.03 | 2.03 |
| 286.38 | 2.80 | 2.80 |
| 318.38 | 1.82 | 1.82 |
| 350.42 | 3.13 | 3.13 |
| 364.45 | 3.38 | 3.38 |
| 292.34 | 3.02 | 3.02 |
| 334.42 | 3.24 | 3.24 |
| 378.48 | 3.64 | 3.64 |
| 452.56 | 3.89 | 3.89 |
| 438.53 | 3.50 | 3.50 |
| 408.50 | 3.49 | 3.49 |
| 394.48 | 3.48 | 3.48 |
| 330.43 | 3.20 | 3.20 |
| 316.41 | 2.81 | 2.81 |