Assay Report Card

Basic Information

ID: ALA669613

Type: Binding

Description: Inhibitory activity against dihydrofolate reductase isolated from murine L5178Y tumor cells resistant to methotrexate.

Cell type: L5178Y

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
289.341.051.05
231.301.181.18
247.300.880.88
235.271.011.01
285.271.891.89
217.280.870.87
259.311.071.07
343.171.481.48
296.171.631.63
289.382.052.05
296.36-0.48-0.48
251.721.531.53
273.382.172.17
233.280.580.58
426.744.414.41
429.655.955.95
387.574.784.78
359.524.004.00
317.442.832.83
260.30-0.03-0.03
385.605.345.34
343.524.174.17
245.331.431.43
261.331.271.27
301.442.992.99
415.635.565.56
401.605.175.17
286.172.182.18
303.412.442.44
275.361.661.66
245.331.491.49
261.331.271.27
289.382.052.05
345.493.613.61
273.341.441.44