Basic Information
ID: ALA671172
Type: Functional
Description: In vivo antagonism activity against dopamine D2 receptor was measured as emesis in dog when administered subcutaneously
Activity Charts
Bioactivity
Activity Types for Assay ALA671172
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 299.80 | 2.00 | 2.00 |
| 325.84 | 2.56 | 2.56 |
| 339.87 | 2.95 | 2.95 |
| 339.87 | 2.95 | 2.95 |
| 365.86 | 3.34 | 3.34 |
| 337.85 | 3.36 | 3.36 |
| 371.44 | 1.69 | 1.69 |
| 301.35 | 1.04 | 1.04 |
| 315.38 | 1.35 | 1.35 |
| 357.88 | 2.14 | 2.14 |
| 367.88 | 2.49 | 2.49 |
| 419.95 | 2.98 | 2.98 |
| 355.87 | 2.35 | 2.35 |
| 381.90 | 2.88 | 2.88 |
| 373.88 | 1.38 | 1.38 |
| 359.85 | 0.73 | 0.73 |
| 318.87 | 2.77 | 2.77 |
| 328.84 | 2.17 | 2.17 |
| 403.91 | 3.26 | 3.26 |
| 341.84 | 1.96 | 1.96 |
| 381.90 | 2.91 | 2.91 |
| 369.89 | 2.74 | 2.74 |
| 373.88 | 1.99 | 1.99 |
| 397.95 | 3.33 | 3.33 |
| 369.89 | 2.74 | 2.74 |
| 369.89 | 2.74 | 2.74 |
| 355.87 | 2.35 | 2.35 |
| 397.95 | 3.33 | 3.33 |
| 357.88 | 2.41 | 2.41 |
| 313.83 | 2.34 | 2.34 |
| 285.77 | 1.70 | 1.70 |
| 323.82 | 2.01 | 2.01 |
| 373.88 | 1.99 | 1.99 |
| 343.86 | 2.02 | 2.02 |
| 357.88 | 2.14 | 2.14 |
| 357.88 | 2.14 | 2.14 |
| 339.87 | 2.95 | 2.95 |
| 371.91 | 2.80 | 2.80 |
| 367.88 | 1.37 | 1.37 |
| 369.89 | 2.74 | 2.74 |
| 357.84 | 1.55 | 1.55 |
| 338.84 | 2.28 | 2.28 |
| 324.81 | 1.90 | 1.90 |
| 399.92 | 2.52 | 2.52 |
| 387.91 | 2.04 | 2.04 |
| 371.87 | 1.75 | 1.75 |
| 341.84 | 1.77 | 1.77 |
| 339.87 | 2.93 | 2.93 |
| 343.86 | 1.75 | 1.75 |
| 369.89 | 2.60 | 2.60 |
| 375.90 | 3.57 | 3.57 |
| 329.83 | 1.36 | 1.36 |
| 311.81 | 2.10 | 2.10 |
| 337.85 | 3.35 | 3.35 |
| 355.87 | 2.16 | 2.16 |
| 341.84 | 1.77 | 1.77 |
| 327.86 | 2.78 | 2.78 |
| 399.92 | 2.53 | 2.53 |
| 370.88 | 2.61 | 2.61 |
| 356.85 | 2.22 | 2.22 |
| 383.92 | 2.68 | 2.68 |
| 376.89 | 2.97 | 2.97 |
| 369.89 | 2.55 | 2.55 |
| 380.88 | 2.87 | 2.87 |
| 425.92 | 3.35 | 3.35 |
| 336.26 | 2.04 | 2.04 |
| 417.94 | 3.18 | 3.18 |
| 343.86 | 1.75 | 1.75 |