Basic Information
ID: ALA675993
Type: Binding
Description: Inhibitory activity against Dual specificity mitogen-activated protein kinase kinase using direct MEK assay (which by-passes the need for activated Raf by using an activated GST-MEK)
Activity Charts
Bioactivity
Activity Types for Assay ALA675993
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.44 | 5.53 | 5.53 |
| 509.61 | 4.95 | 4.95 |
| 397.43 | 5.66 | 5.66 |
| 396.45 | 5.61 | 5.61 |
| 395.46 | 5.46 | 5.46 |
| 431.88 | 6.31 | 6.31 |
| 514.65 | 5.61 | 5.61 |
| 514.65 | 5.61 | 5.61 |
| 511.58 | 5.15 | 5.15 |
| 509.61 | 4.95 | 4.95 |
| 498.58 | 5.14 | 5.14 |
| 510.59 | 5.75 | 5.75 |
| 397.43 | 5.66 | 5.66 |
| 508.62 | 5.55 | 5.55 |
| 351.43 | 4.59 | 4.59 |
| 321.34 | 3.57 | 3.57 |
| 335.36 | 3.88 | 3.88 |
| 516.64 | 5.67 | 5.67 |
| 526.66 | 6.11 | 6.11 |
| 448.52 | 3.97 | 3.97 |
| 514.67 | 6.08 | 6.08 |
| 509.61 | 4.95 | 4.95 |
| 498.58 | 5.14 | 5.14 |
| 532.71 | 6.38 | 6.38 |
| 397.43 | 5.66 | 5.66 |