Basic Information
ID: ALA676569
Type: Binding
Description: Ability to inhibit Endothelin A receptor induced contractions in rabbit carotid artery rings (ETA) was determined in an in vitro functional assay.
Organism: Oryctolagus cuniculus
Tissue: Artery
Activity Charts
Bioactivity
Activity Types for Assay ALA676569
Kb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 345.42 | 3.31 | 3.31 |
| 328.39 | 3.76 | 3.76 |
| 399.52 | 4.54 | 4.54 |
| 384.50 | 4.96 | 4.96 |
| 400.50 | 4.66 | 4.66 |
| 402.49 | 5.10 | 5.10 |
| 400.50 | 4.66 | 4.66 |
| 464.47 | 4.42 | 4.42 |
| 414.53 | 4.97 | 4.97 |
| 427.53 | 4.53 | 4.53 |
| 456.57 | 4.71 | 4.71 |
| 444.55 | 4.33 | 4.33 |
| 399.52 | 4.54 | 4.54 |
| 399.52 | 4.60 | 4.60 |
| 343.41 | 3.34 | 3.34 |
| 385.49 | 4.58 | 4.58 |
| 370.47 | 4.71 | 4.71 |
| 457.55 | 4.45 | 4.45 |
| 398.53 | 5.35 | 5.35 |
| 398.53 | 5.35 | 5.35 |
| 342.42 | 4.07 | 4.07 |
| 443.57 | 4.36 | 4.36 |
| 441.60 | 5.78 | 5.78 |
| 370.47 | 4.88 | 4.88 |
| 384.50 | 4.96 | 4.96 |
| 384.50 | 5.06 | 5.06 |
| 384.50 | 5.10 | 5.10 |
| 427.53 | 4.06 | 4.06 |
| 441.60 | 5.78 | 5.78 |
| 371.46 | 3.83 | 3.83 |
| 371.46 | 3.83 | 3.83 |
| 414.53 | 4.45 | 4.45 |
| 398.53 | 5.27 | 5.27 |
| 358.42 | 3.25 | 3.25 |
| 441.55 | 4.20 | 4.20 |
| 457.55 | 4.45 | 4.45 |
| 413.54 | 5.00 | 5.00 |
| 402.54 | 5.26 | 5.26 |
| 427.57 | 5.39 | 5.39 |
| 400.50 | 4.79 | 4.79 |
| 386.47 | 4.55 | 4.55 |
| 358.42 | 3.77 | 3.77 |