Basic Information
ID: ALA678329
Type: Binding
Description: Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2
Activity Charts
Bioactivity
Activity Types for Assay ALA678329
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.75 | 2.29 | 2.29 |
| 303.29 | 1.77 | 1.77 |
| 284.75 | 3.15 | 3.15 |
| 326.32 | 2.58 | 2.58 |
| 354.37 | 3.36 | 3.36 |
| 345.79 | 2.68 | 2.68 |
| 285.30 | 1.63 | 1.63 |
| 370.43 | 3.15 | 3.15 |
| 358.35 | 2.32 | 2.32 |
| 439.25 | 3.02 | 3.02 |
| 347.80 | 3.07 | 3.07 |
| 392.25 | 3.18 | 3.18 |
| 331.38 | 4.07 | 4.07 |
| 284.31 | 2.99 | 2.99 |
| 300.31 | 2.70 | 2.70 |
| 346.39 | 4.42 | 4.42 |
| 374.44 | 4.99 | 4.99 |
| 314.34 | 3.00 | 3.00 |
| 240.26 | 2.84 | 2.84 |
| 275.31 | 2.37 | 2.37 |
| 236.27 | 2.48 | 2.48 |
| 313.29 | 2.55 | 2.55 |
| 278.24 | 3.12 | 3.12 |
| 314.34 | 3.03 | 3.03 |
| 261.28 | 2.77 | 2.77 |
| 343.22 | 4.23 | 4.23 |
| 309.33 | 1.62 | 1.62 |
| 275.74 | 2.67 | 2.67 |
| 360.89 | 3.73 | 3.73 |
| 332.84 | 2.95 | 2.95 |
| 317.82 | 3.84 | 3.84 |
| 329.36 | 2.03 | 2.03 |
| 331.80 | 3.48 | 3.48 |
| 289.72 | 2.31 | 2.31 |
| 277.71 | 1.60 | 1.60 |
| 296.16 | 2.85 | 2.85 |
| 305.77 | 2.65 | 2.65 |
| 291.74 | 2.26 | 2.26 |
| 342.40 | 3.83 | 3.83 |
| 341.37 | 2.35 | 2.35 |
| 307.40 | 3.25 | 3.25 |
| 212.25 | 3.07 | 3.07 |
| 226.28 | 3.46 | 3.46 |
| 202.64 | 3.32 | 3.32 |
| 225.28 | 3.40 | 3.40 |
| 257.30 | 4.35 | 4.35 |
| 395.54 | ||
| 337.38 | 2.39 | 2.39 |
| 313.36 | 2.20 | 2.20 |
| 409.56 | ||
| 323.35 | 2.01 | 2.01 |
| 381.51 | ||
| 323.35 | 2.43 | 2.43 |
| 341.41 | 2.98 | 2.98 |
| 240.31 | 3.85 | 3.85 |
| 226.28 | 3.45 | 3.45 |
| 238.29 | 3.65 | 3.65 |
| 268.32 | 3.62 | 3.62 |
| 250.30 | 2.50 | 2.50 |
| 357.80 | 3.28 | 3.28 |
| 302.29 | 4.21 | 4.21 |
| 363.42 | 5.88 | 5.88 |
| 291.74 | 4.96 | 4.96 |
| 275.29 | 4.44 | 4.44 |
| 300.36 | 3.65 | 3.65 |
| 356.42 | 3.84 | 3.84 |
| 285.35 | 3.23 | 3.23 |
| 328.41 | 4.44 | 4.44 |
| 412.53 | 5.78 | 5.78 |
| 396.53 | 6.19 | 6.19 |
| 286.33 | 3.26 | 3.26 |
| 328.37 | 3.42 | 3.42 |
| 410.56 | 6.20 | 6.20 |
| 426.56 | 5.79 | 5.79 |
| 274.32 | 4.25 | 4.25 |
| 254.33 | 4.09 | 4.09 |
| 282.34 | 3.47 | 3.47 |
| 321.34 | 1.93 | 1.93 |
| 393.52 | ||
| 359.39 | 2.93 | 2.93 |
| 376.21 | 2.71 | 2.71 |
| 335.36 | 2.32 | 2.32 |
| 345.36 | 2.50 | 2.50 |
| 331.34 | 2.11 | 2.11 |
| 343.38 | 2.42 | 2.42 |
| 335.36 | 2.32 | 2.32 |
| 390.24 | 3.10 | 3.10 |
| 407.55 | ||
| 373.42 | 3.32 | 3.32 |
| 359.39 | 2.76 | 2.76 |
| 345.36 | 2.50 | 2.50 |
| 423.59 | ||
| 311.34 | 2.28 | 2.28 |
| 390.24 | 3.10 | 3.10 |
| 345.36 | 2.37 | 2.37 |
| 356.43 | 2.48 | 2.48 |
| 407.55 | ||
| 310.31 | 1.51 | 1.51 |
| 364.20 | 2.40 | 2.40 |
| 396.49 | 3.40 | 3.40 |
| 329.36 | 2.12 | 2.12 |
| 382.46 | 3.01 | 3.01 |
| 287.32 | 4.31 | 4.31 |
| 290.77 | 3.22 | 3.22 |
| 274.71 | 2.75 | 2.75 |
| 340.30 | 2.32 | 2.32 |
| 318.30 | 4.36 | 4.36 |
| 274.32 | 2.70 | 2.70 |
| 283.31 | 3.03 | 3.03 |
| 246.28 | 2.39 | 2.39 |
| 290.77 | 3.22 | 3.22 |
| 260.29 | 2.68 | 2.68 |
| 258.19 | 2.53 | 2.53 |
| 346.51 | ||
| 328.37 | 2.25 | 2.25 |
| 298.34 | 3.42 | 3.42 |
| 292.73 | 4.12 | 4.12 |
| 440.50 | 5.72 | 5.72 |
| 381.44 | 5.22 | 5.22 |
| 323.40 | 4.20 | 4.20 |
| 314.35 | 1.85 | 1.85 |
| 375.45 | 4.97 | 4.97 |
| 258.28 | 3.70 | 3.70 |
| 311.34 | 2.34 | 2.34 |
| 329.20 | 3.26 | 3.26 |
| 360.17 | 3.15 | 3.15 |
| 418.29 | 3.88 | 3.88 |
| 424.50 | 6.14 | 6.14 |
| 258.28 | 3.70 | 3.70 |
| 282.35 | 3.86 | 3.86 |
| 274.32 | 2.48 | 2.48 |
| 258.28 | 3.52 | 3.52 |
| 258.28 | 3.70 | 3.70 |
| 404.47 | 5.01 | 5.01 |
| 240.31 | 3.75 | 3.75 |
| 390.44 | 4.62 | 4.62 |
| 321.34 | 2.88 | 2.88 |
| 295.73 | 3.52 | 3.52 |
| 291.31 | 2.88 | 2.88 |
| 285.31 | 2.85 | 2.85 |
| 340.18 | 3.63 | 3.63 |
| 340.18 | 3.63 | 3.63 |
| 325.76 | 3.53 | 3.53 |
| 357.49 | ||
| 291.31 | 2.88 | 2.88 |
| 285.31 | 2.85 | 2.85 |