Basic Information
ID: ALA678443
Type: Binding
Description: Inhibition of A-beta-42 production by inhibiting Gamma-secretase proteolytic pathway in HEK293 cell stably transfected with a double mutant form of human APP(K595N/M596L)
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA678443
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 299.46 | 3.24 | 3.24 |
| 311.42 | 3.32 | 3.32 |
| 311.42 | 3.32 | 3.32 |
| 372.33 | 3.94 | 3.94 |
| 327.88 | 3.83 | 3.83 |