Basic Information
ID: ALA678605
Type: Binding
Description: In vitro efficacy by [35S]t-butyl-bicyclophosphorothionate (TBPS) binding to the picrotoxin convulsant site on the GABA-A receptor chloride complex.
Activity Charts
Bioactivity
Activity Types for Assay ALA678605
TBPS shift
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.75 | 3.15 | 3.15 |
| 335.37 | 3.16 | 3.16 |
| 360.46 | 4.58 | 4.58 |
| 358.45 | 4.47 | 4.47 |
| 412.85 | 4.10 | 4.10 |
| 364.42 | 4.51 | 4.51 |
| 336.37 | 3.73 | 3.73 |
| 308.32 | 3.08 | 3.08 |
| 364.37 | 2.11 | 2.11 |
| 303.37 | 3.90 | 3.90 |
| 364.42 | 4.42 | 4.42 |
| 346.43 | 4.28 | 4.28 |
| 351.38 | 4.54 | 4.54 |
| 387.39 | 4.98 | 4.98 |
| 387.39 | 4.98 | 4.98 |
| 386.50 | 5.12 | 5.12 |
| 323.33 | 3.76 | 3.76 |
| 390.46 | 4.95 | 4.95 |
| 321.36 | 4.04 | 4.04 |
| 333.39 | 3.91 | 3.91 |
| 321.36 | 4.04 | 4.04 |
| 337.81 | 4.55 | 4.55 |
| 317.39 | 4.21 | 4.21 |
| 371.36 | 4.92 | 4.92 |
| 371.36 | 4.92 | 4.92 |
| 439.92 | 4.45 | 4.45 |
| 396.40 | 3.59 | 3.59 |
| 335.38 | 4.34 | 4.34 |
| 333.39 | 3.91 | 3.91 |
| 431.54 | 4.01 | 4.01 |
| 417.51 | 3.67 | 3.67 |
| 453.95 | 4.80 | 4.80 |
| 347.42 | 4.21 | 4.21 |
| 437.49 | 4.28 | 4.28 |
| 339.35 | 4.18 | 4.18 |
| 355.80 | 4.69 | 4.69 |
| 367.84 | 4.56 | 4.56 |
| 355.80 | 4.69 | 4.69 |
| 351.38 | 4.04 | 4.04 |
| 358.45 | 4.38 | 4.38 |
| 362.41 | 4.21 | 4.21 |
| 321.36 | 4.04 | 4.04 |
| 419.50 | 4.14 | 4.14 |
| 405.48 | 3.80 | 3.80 |
| 378.41 | 3.45 | 3.45 |
| 344.42 | 4.08 | 4.08 |
| 336.37 | 3.68 | 3.68 |
| 423.47 | 3.94 | 3.94 |
| 412.85 | 4.10 | 4.10 |
| 318.38 | 3.54 | 3.54 |
| 387.39 | 4.98 | 4.98 |