Assay Report Card

Basic Information

ID: ALA678614

Type: Binding

Description: Inhibition of A-beta-42 production by inhibiting Gamma-secretase proteolytic pathway in HEK293 cell stably transfected with a double mutant form of human APP(K595N/M596L), at 2.5 uM concentration

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
299.463.243.24
311.423.323.32
311.423.323.32
311.423.323.32
372.333.943.94
327.883.833.83
311.423.323.32
311.423.323.32