Basic Information
ID: ALA679119
Type: Binding
Description: In vitro inhibition of endothelin binding to endothelin A receptor in rat heart ventricles was measured using a 125-I labelled ET-1 competition assay
Activity Charts
Bioactivity
Activity Types for Assay ALA679119
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.47 | 4.62 | 4.62 |
| 476.92 | 5.28 | 5.28 |
| 464.40 | 3.74 | 3.74 |
| 492.45 | 4.52 | 4.52 |
| 450.41 | 3.65 | 3.65 |
| 406.36 | 3.57 | 3.57 |
| 410.78 | 4.22 | 4.22 |
| 420.34 | 3.29 | 3.29 |
| 380.34 | 3.98 | 3.98 |
| 396.80 | 4.50 | 4.50 |
| 440.81 | 4.23 | 4.23 |
| 392.33 | 3.27 | 3.27 |
| 506.37 | 4.84 | 4.84 |
| 458.51 | 4.15 | 4.15 |
| 406.36 | 3.57 | 3.57 |
| 414.46 | 4.22 | 4.22 |
| 480.40 | 3.04 | 3.04 |
| 440.81 | 4.23 | 4.23 |
| 392.38 | 3.85 | 3.85 |
| 456.37 | 4.21 | 4.21 |
| 406.36 | 3.57 | 3.57 |
| 450.37 | 3.03 | 3.03 |
| 431.24 | 5.15 | 5.15 |
| 410.78 | 4.22 | 4.22 |
| 362.35 | 3.84 | 3.84 |
| 376.33 | 3.56 | 3.56 |
| 352.39 | 2.86 | 2.86 |
| 459.46 | 4.13 | 4.13 |