Basic Information
ID: ALA679284
Type: Binding
Description: Binding affinity for endothelin A receptor by inhibition of [125I]ET1 binding in rat aorta smooth muscle cells
Tissue: Aorta
Activity Charts
Bioactivity
Activity Types for Assay ALA679284
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.47 | 4.95 | 4.95 |
| 432.43 | 4.45 | 4.45 |
| 416.39 | 4.16 | 4.16 |
| 460.48 | 5.23 | 5.23 |
| 446.50 | 5.51 | 5.51 |
| 460.48 | 5.23 | 5.23 |
| 398.41 | 4.17 | 4.17 |
| 508.53 | 6.02 | 6.02 |
| 476.53 | 5.52 | 5.52 |
| 476.53 | 5.52 | 5.52 |
| 448.47 | 4.91 | 4.91 |
| 422.48 | 5.36 | 5.36 |
| 476.48 | 5.22 | 5.22 |
| 396.44 | 4.83 | 4.83 |
| 504.54 | 5.63 | 5.63 |
| 504.54 | 5.63 | 5.63 |
| 426.47 | 4.34 | 4.34 |
| 476.48 | 4.20 | 4.20 |
| 504.54 | 5.63 | 5.63 |
| 426.47 | 4.60 | 4.60 |
| 424.49 | 5.61 | 5.61 |
| 438.52 | 6.14 | 6.14 |
| 410.47 | 5.36 | 5.36 |
| 474.47 | 4.95 | 4.95 |
| 424.49 | 5.75 | 5.75 |
| 354.36 | 3.80 | 3.80 |
| 458.55 | 6.63 | 6.63 |
| 296.28 | 3.02 | 3.02 |
| 412.44 | 4.56 | 4.56 |
| 426.47 | 4.95 | 4.95 |
| 432.43 | 4.45 | 4.45 |
| 460.48 | 5.23 | 5.23 |
| 444.48 | 5.57 | 5.57 |
| 440.49 | 5.34 | 5.34 |
| 426.47 | 4.95 | 4.95 |
| 386.40 | 4.74 | 4.74 |
| 460.48 | 5.23 | 5.23 |
| 438.48 | 5.11 | 5.11 |
| 406.82 | 5.09 | 5.09 |
| 414.46 | 5.56 | 5.56 |
| 460.48 | 5.23 | 5.23 |
| 460.48 | 5.23 | 5.23 |
| 412.44 | 4.56 | 4.56 |
| 510.63 | 7.29 | 7.29 |
| 368.39 | 4.16 | 4.16 |
| 354.36 | 3.77 | 3.77 |
| 460.48 | 5.23 | 5.23 |
| 410.47 | 5.36 | 5.36 |
| 340.33 | 3.38 | 3.38 |
| 487.57 | 4.36 | 4.36 |
| 398.41 | 4.17 | 4.17 |
| 384.38 | 3.78 | 3.78 |
| 354.36 | 3.80 | 3.80 |
| 402.40 | 4.44 | 4.44 |
| 402.40 | 4.44 | 4.44 |
| 372.38 | 4.44 | 4.44 |
| 474.51 | 5.62 | 5.62 |
| 430.46 | 5.22 | 5.22 |
| 460.48 | 5.23 | 5.23 |
| 388.80 | 4.37 | 4.37 |
| 434.50 | 4.95 | 4.95 |
| 528.60 | 6.94 | 6.94 |
| 474.51 | 5.62 | 5.62 |
| 459.50 | 4.63 | 4.63 |
| 448.45 | 5.36 | 5.36 |
| 516.59 | 6.79 | 6.79 |
| 382.41 | 4.55 | 4.55 |
| 472.54 | 6.35 | 6.35 |
| 460.48 | 5.23 | 5.23 |
| 474.47 | 4.95 | 4.95 |
| 472.54 | 6.35 | 6.35 |
| 450.53 | 6.14 | 6.14 |
| 446.46 | 4.93 | 4.93 |
| 384.38 | 3.78 | 3.78 |
| 354.36 | 3.80 | 3.80 |
| 462.50 | 5.18 | 5.18 |
| 409.48 | 4.77 | 4.77 |
| 424.49 | 5.45 | 5.45 |
| 450.51 | 5.59 | 5.59 |
| 474.51 | 5.43 | 5.43 |
| 442.53 | 5.67 | 5.67 |
| 474.51 | 5.62 | 5.62 |
| 446.46 | 4.84 | 4.84 |
| 437.45 | 4.45 | 4.45 |
| 456.49 | 4.31 | 4.31 |
| 426.47 | 4.95 | 4.95 |
| 474.51 | 5.32 | 5.32 |
| 412.44 | 4.56 | 4.56 |
| 537.59 | 4.22 | 4.22 |
| 412.48 | 5.31 | 5.31 |
| 536.58 | 6.80 | 6.80 |
| 504.54 | 5.40 | 5.40 |
| 468.55 | 6.12 | 6.12 |
| 454.52 | 5.73 | 5.73 |
| 440.49 | 5.34 | 5.34 |
| 402.40 | 4.44 | 4.44 |
| 474.51 | 5.62 | 5.62 |