Basic Information
ID: ALA679716
Type: Binding
Description: The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.
Activity Charts
Bioactivity
Activity Types for Assay ALA679716
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 598.70 | 0.73 | 0.73 |
| 650.74 | 0.29 | 0.29 |
| 638.72 | 0.34 | 0.34 |
| 710.83 | 2.09 | 2.09 |
| 624.74 | 1.37 | 1.37 |
| 641.77 | 0.45 | 0.45 |
| 627.74 | 0.06 | 0.06 |
| 664.74 | -0.79 | -0.79 |
| 598.70 | 0.69 | 0.69 |
| 598.70 | 0.73 | 0.73 |
| 612.73 | 1.12 | 1.12 |
| 699.81 | 2.05 | 2.05 |
| 624.74 | 1.22 | 1.22 |
| 660.77 | 1.57 | 1.57 |
| 644.80 | 1.08 | 1.08 |
| 596.69 | 0.59 | 0.59 |
| 586.60 | -1.23 | -1.23 |
| 624.74 | 1.17 | 1.17 |
| 610.71 | 0.98 | 0.98 |
| 584.67 | 0.34 | 0.34 |
| 570.65 | -0.04 | -0.04 |
| 624.74 | 0.92 | 0.92 |
| 669.78 | -0.62 | -0.62 |
| 636.75 | 1.37 | 1.37 |
| 624.74 | 1.22 | 1.22 |
| 642.78 | 0.88 | 0.88 |
| 642.71 | -0.05 | -0.05 |
| 587.67 | 0.06 | 0.06 |
| 568.63 | -0.20 | -0.20 |
| 628.68 | -0.20 | -0.20 |
| 582.66 | 0.19 | 0.19 |
| 616.63 | -1.86 | -1.86 |
| 642.71 | 0.19 | 0.19 |
| 641.73 | -0.41 | -0.41 |
| 610.71 | 0.83 | 0.83 |
| 610.71 | 0.98 | 0.98 |
| 668.75 | 0.92 | 0.92 |
| 646.77 | 0.24 | 0.24 |
| 584.67 | 0.30 | 0.30 |
| 628.75 | 0.74 | 0.74 |
| 616.74 | 0.25 | 0.25 |
| 624.74 | 1.22 | 1.22 |
| 558.59 | -1.71 | -1.71 |
| 600.67 | -0.68 | -0.68 |
| 598.70 | 0.73 | 0.73 |
| 612.73 | 0.98 | 0.98 |
| 626.76 | 1.37 | 1.37 |
| 596.73 | 0.74 | 0.74 |
| 571.68 | 0.35 | 0.35 |
| 561.64 | -0.93 | -0.93 |
| 638.77 | 1.61 | 1.61 |
| 650.76 | 1.61 | 1.61 |
| 646.75 | 1.45 | 1.45 |
| 644.73 | 1.55 | 1.55 |
| 624.74 | 1.27 | 1.27 |
| 614.70 | -0.29 | -0.29 |
| 610.71 | 0.83 | 0.83 |
| 624.74 | 1.22 | 1.22 |
| 586.65 | -0.93 | -0.93 |
| 626.71 | -0.20 | -0.20 |
| 624.74 | 1.22 | 1.22 |
| 596.69 | 0.44 | 0.44 |
| 598.70 | 0.73 | 0.73 |
| 598.70 | 0.73 | 0.73 |
| 598.70 | 0.73 | 0.73 |