Assay Report Card

Basic Information

ID: ALA682251

Type: Binding

Description: Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2

Activity Charts

Bioactivity

Activity Types for Assay ALA682251

Ki

Total(146)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
319.75	2.29	2.29
303.29	1.77	1.77
284.75	3.15	3.15
326.32	2.58	2.58
354.37	3.36	3.36
345.79	2.68	2.68
285.30	1.63	1.63
370.43	3.15	3.15
358.35	2.32	2.32
439.25	3.02	3.02
347.80	3.07	3.07
392.25	3.18	3.18
331.38	4.07	4.07
284.31	2.99	2.99
300.31	2.70	2.70
346.39	4.42	4.42
374.44	4.99	4.99
314.34	3.00	3.00
240.26	2.84	2.84
275.31	2.37	2.37
236.27	2.48	2.48
313.29	2.55	2.55
278.24	3.12	3.12
314.34	3.03	3.03
261.28	2.77	2.77
343.22	4.23	4.23
309.33	1.62	1.62
275.74	2.67	2.67
360.89	3.73	3.73
332.84	2.95	2.95
317.82	3.84	3.84
329.36	2.03	2.03
331.80	3.48	3.48
289.72	2.31	2.31
277.71	1.60	1.60
296.16	2.85	2.85
305.77	2.65	2.65
291.74	2.26	2.26
342.40	3.83	3.83
341.37	2.35	2.35
307.40	3.25	3.25
212.25	3.07	3.07
226.28	3.46	3.46
202.64	3.32	3.32
225.28	3.40	3.40
257.30	4.35	4.35
395.54
337.38	2.39	2.39
313.36	2.20	2.20
409.56
323.35	2.01	2.01
381.51
323.35	2.43	2.43
341.41	2.98	2.98
240.31	3.85	3.85
226.28	3.45	3.45
238.29	3.65	3.65
268.32	3.62	3.62
250.30	2.50	2.50
357.80	3.28	3.28
302.29	4.21	4.21
363.42	5.88	5.88
291.74	4.96	4.96
275.29	4.44	4.44
300.36	3.65	3.65
356.42	3.84	3.84
285.35	3.23	3.23
328.41	4.44	4.44
412.53	5.78	5.78
396.53	6.19	6.19
286.33	3.26	3.26
328.37	3.42	3.42
410.56	6.20	6.20
426.56	5.79	5.79
274.32	4.25	4.25
254.33	4.09	4.09
282.34	3.47	3.47
321.34	1.93	1.93
393.52
359.39	2.93	2.93
376.21	2.71	2.71
335.36	2.32	2.32
345.36	2.50	2.50
331.34	2.11	2.11
343.38	2.42	2.42
335.36	2.32	2.32
390.24	3.10	3.10
407.55
373.42	3.32	3.32
359.39	2.76	2.76
345.36	2.50	2.50
423.59
311.34	2.28	2.28
390.24	3.10	3.10
345.36	2.37	2.37
356.43	2.48	2.48
407.55
310.31	1.51	1.51
364.20	2.40	2.40
396.49	3.40	3.40
329.36	2.12	2.12
382.46	3.01	3.01
287.32	4.31	4.31
290.77	3.22	3.22
274.71	2.75	2.75
340.30	2.32	2.32
318.30	4.36	4.36
274.32	2.70	2.70
283.31	3.03	3.03
246.28	2.39	2.39
290.77	3.22	3.22
260.29	2.68	2.68
258.19	2.53	2.53
346.51
328.37	2.25	2.25
298.34	3.42	3.42
292.73	4.12	4.12
440.50	5.72	5.72
381.44	5.22	5.22
323.40	4.20	4.20
314.35	1.85	1.85
375.45	4.97	4.97
258.28	3.70	3.70
311.34	2.34	2.34
329.20	3.26	3.26
360.17	3.15	3.15
418.29	3.88	3.88
424.50	6.14	6.14
258.28	3.70	3.70
282.35	3.86	3.86
274.32	2.48	2.48
258.28	3.52	3.52
258.28	3.70	3.70
404.47	5.01	5.01
240.31	3.75	3.75
390.44	4.62	4.62
321.34	2.88	2.88
295.73	3.52	3.52
291.31	2.88	2.88
285.31	2.85	2.85
340.18	3.63	3.63
340.18	3.63	3.63
325.76	3.53	3.53
357.49
291.31	2.88	2.88
285.31	2.85	2.85