Basic Information
ID: ALA682431
Type: Functional
Description: Antibacterial activity against five Gram-positive bacteria targeting topoisomerase II (DNA gyrase B GyrB)
Activity Charts
Bioactivity
Activity Types for Assay ALA682431
MIC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.37 | 1.54 | 1.54 |
| 369.34 | 1.70 | 1.70 |
| 379.41 | 2.43 | 2.43 |
| 391.42 | 2.75 | 2.75 |
| 433.38 | 2.98 | 2.98 |
| 331.35 | 1.58 | 1.58 |
| 405.45 | 2.82 | 2.82 |
| 380.40 | 1.59 | 1.59 |
| 319.34 | 1.27 | 1.27 |
| 397.40 | 2.38 | 2.38 |
| 333.36 | 1.61 | 1.61 |
| 359.40 | 2.36 | 2.36 |
| 403.36 | 2.52 | 2.52 |
| 445.44 | 3.54 | 3.54 |
| 364.35 | 1.43 | 1.43 |
| 346.36 | 1.29 | 1.29 |
| 337.33 | 1.54 | 1.54 |
| 389.43 | 2.37 | 2.37 |
| 376.39 | 1.30 | 1.30 |
| 363.36 | 2.10 | 2.10 |
| 373.43 | 2.61 | 2.61 |
| 349.34 | 1.85 | 1.85 |
| 374.42 | 2.00 | 2.00 |
| 404.35 | 2.04 | 2.04 |
| 399.34 | 2.73 | 2.73 |
| 361.37 | 1.59 | 1.59 |
| 331.35 | 1.71 | 1.71 |
| 375.40 | 2.11 | 2.11 |
| 361.37 | 1.72 | 1.72 |
| 365.79 | 2.36 | 2.36 |
| 388.44 | 2.19 | 2.19 |
| 375.40 | 1.97 | 1.97 |
| 345.37 | 1.96 | 1.96 |
| 332.33 | 1.11 | 1.11 |
| 346.36 | 1.35 | 1.35 |
| 360.39 | 1.74 | 1.74 |
| 359.40 | 2.35 | 2.35 |
| 441.43 | 3.63 | 3.63 |
| 403.45 | 2.62 | 2.62 |
| 389.43 | 2.36 | 2.36 |
| 379.82 | 2.63 | 2.63 |
| 349.34 | 1.72 | 1.72 |
| 365.79 | 2.24 | 2.24 |
| 365.34 | 1.56 | 1.56 |
| 377.39 | 2.50 | 2.50 |
| 407.87 | 3.26 | 3.26 |
| 380.81 | 1.95 | 1.95 |
| 347.35 | 1.42 | 1.42 |
| 361.42 | 2.29 | 2.29 |
| 377.39 | 2.49 | 2.49 |
| 359.40 | 2.27 | 2.27 |
| 405.45 | 3.06 | 3.06 |
| 363.36 | 2.16 | 2.16 |
| 345.37 | 2.02 | 2.02 |
| 332.34 | 0.98 | 0.98 |
| 393.85 | 3.01 | 3.01 |
| 399.34 | 2.60 | 2.60 |
| 427.40 | 3.37 | 3.37 |
| 363.36 | 2.24 | 2.24 |
| 413.37 | 3.12 | 3.12 |
| 345.37 | 2.10 | 2.10 |
| 413.37 | 3.12 | 3.12 |
| 363.36 | 2.24 | 2.24 |
| 345.37 | 2.10 | 2.10 |
| 346.36 | 1.50 | 1.50 |
| 379.82 | 2.75 | 2.75 |
| 393.85 | 3.00 | 3.00 |
| 417.33 | 2.87 | 2.87 |
| 427.40 | 3.38 | 3.38 |
| 377.44 | 2.43 | 2.43 |
| 485.38 | 3.92 | 3.92 |
| 451.83 | 3.56 | 3.56 |
| 485.38 | 4.05 | 4.05 |
| 407.87 | 3.26 | 3.26 |
| 403.45 | 2.62 | 2.62 |
| 391.42 | 2.75 | 2.75 |
| 433.39 | 2.65 | 2.65 |
| 373.43 | 2.61 | 2.61 |
| 413.37 | 3.04 | 3.04 |
| 384.33 | 3.79 | 3.79 |
| 346.36 | 2.78 | 2.78 |
| 350.78 | 3.43 | 3.43 |
| 395.41 | 1.41 | 1.41 |
| 447.41 | 3.04 | 3.04 |
| 479.89 | 4.20 | 4.20 |
| 413.37 | 3.12 | 3.12 |
| 317.32 | 2.17 | 2.17 |
| 413.37 | 2.98 | 2.98 |
| 316.33 | 2.77 | 2.77 |
| 377.44 | 2.43 | 2.43 |
| 375.40 | 2.11 | 2.11 |
| 334.32 | 2.91 | 2.91 |
| 363.36 | 2.02 | 2.02 |
| 413.37 | 2.99 | 2.99 |
| 442.32 | 3.92 | 3.92 |
| 448.47 | 2.71 | 2.71 |
| 346.36 | 1.29 | 1.29 |
| 362.41 | 1.45 | 1.45 |
| 420.46 | 2.79 | 2.79 |
| 409.41 | 2.89 | 2.89 |
| 335.31 | 1.62 | 1.62 |
| 367.33 | 1.99 | 1.99 |
| 346.36 | 1.50 | 1.50 |
| 400.24 | 3.02 | 3.02 |
| 395.82 | 2.37 | 2.37 |
| 471.36 | 3.66 | 3.66 |
| 437.81 | 3.30 | 3.30 |
| 379.82 | 2.75 | 2.75 |
| 360.39 | 1.76 | 1.76 |
| 376.34 | 1.62 | 1.62 |
| 441.43 | 3.63 | 3.63 |
| 374.42 | 2.00 | 2.00 |
| 379.82 | 2.61 | 2.61 |
| 418.43 | 2.52 | 2.52 |
| 387.45 | 2.92 | 2.92 |
| 388.44 | 2.19 | 2.19 |