Basic Information
ID: ALA683165
Type: Functional
Description: Cytotoxicity measured using the drug resistant, P-glycoprotein (Pgp) expressing human small cell lung carcinoma cell line H69/LX4
Organism: Homo sapiens
Cell type: NCI-H69
Activity Charts
Bioactivity
Activity Types for Assay ALA683165
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.45 | 1.85 | 1.85 |
| 543.53 | 0.00 | 0.00 |
| 388.47 | 3.62 | 3.62 |
| 416.48 | 3.01 | 3.01 |
| 388.47 | 3.62 | 3.62 |
| 431.50 | 3.34 | 3.34 |
| 402.45 | 3.15 | 3.15 |
| 437.53 | 2.60 | 2.60 |
| 376.42 | 1.99 | 1.99 |
| 431.54 | 3.17 | 3.17 |
| 414.51 | 4.16 | 4.16 |
| 402.50 | 4.02 | 4.02 |
| 401.47 | 3.19 | 3.19 |
| 416.53 | 4.26 | 4.26 |
| 423.31 | 3.99 | 3.99 |
| 362.41 | 3.37 | 3.37 |
| 388.43 | 2.93 | 2.93 |
| 387.49 | 3.29 | 3.29 |
| 398.47 | 3.16 | 3.16 |
| 402.50 | 4.01 | 4.01 |
| 378.86 | 3.88 | 3.88 |
| 376.42 | 2.64 | 2.64 |
| 404.47 | 3.24 | 3.24 |
| 404.47 | 3.24 | 3.24 |
| 434.50 | 1.96 | 1.96 |
| 404.47 | 3.24 | 3.24 |
| 344.42 | 3.23 | 3.23 |
| 389.42 | 3.14 | 3.14 |
| 389.42 | 3.14 | 3.14 |
| 445.57 | 3.56 | 3.56 |
| 473.58 | 2.94 | 2.94 |
| 427.51 | 3.91 | 3.91 |
| 388.47 | 3.54 | 3.54 |
| 374.44 | 3.24 | 3.24 |
| 389.42 | 3.14 | 3.14 |
| 374.44 | 3.24 | 3.24 |
| 360.42 | 2.93 | 2.93 |
| 464.57 | 4.85 | 4.85 |
| 446.51 | 3.17 | 3.17 |
| 404.47 | 2.60 | 2.60 |
| 418.50 | 2.99 | 2.99 |
| 360.42 | 2.93 | 2.93 |
| 404.47 | 2.60 | 2.60 |
| 418.50 | 2.99 | 2.99 |
| 347.42 | 3.52 | 3.52 |
| 418.45 | 2.69 | 2.69 |
| 432.48 | 2.78 | 2.78 |
| 388.47 | 3.63 | 3.63 |
| 403.49 | 3.28 | 3.28 |
| 389.46 | 2.82 | 2.82 |
| 374.44 | 3.24 | 3.24 |
| 360.42 | 2.93 | 2.93 |
| 390.44 | 2.94 | 2.94 |
| 359.43 | 2.81 | 2.81 |
| 374.44 | 2.72 | 2.72 |
| 360.42 | 2.89 | 2.89 |
| 402.50 | 4.01 | 4.01 |
| 388.47 | 3.62 | 3.62 |
| 400.48 | 3.77 | 3.77 |
| 422.51 | 2.63 | 2.63 |
| 390.51 | 3.95 | 3.95 |
| 437.53 | 2.14 | 2.14 |
| 453.34 | 4.00 | 4.00 |
| 408.89 | 3.89 | 3.89 |
| 416.48 | 3.20 | 3.20 |
| 399.45 | 3.13 | 3.13 |
| 398.47 | 3.24 | 3.24 |
| 450.54 | 4.81 | 4.81 |
| 418.45 | 2.69 | 2.69 |
| 417.47 | 2.09 | 2.09 |
| 418.50 | 3.25 | 3.25 |
| 388.47 | 3.63 | 3.63 |
| 515.62 | 1.95 | 1.95 |
| 402.50 | 4.01 | 4.01 |
| 404.47 | 2.60 | 2.60 |
| 386.46 | 3.38 | 3.38 |
| 416.53 | 4.26 | 4.26 |
| 388.47 | 3.62 | 3.62 |
| 402.45 | 3.01 | 3.01 |
| 369.43 | 3.10 | 3.10 |
| 358.45 | 3.54 | 3.54 |