Basic Information
ID: ALA683658
Type: Binding
Description: Concentration required to inhibit recombinant human geranylgeranyl transferase type I (GGTase-I) catalyzed incorporation of [3H]GGPP to the C-terminus of human K-Ras.
Activity Charts
Bioactivity
Activity Types for Assay ALA683658
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.54 | 4.89 | 4.89 |
| 471.61 | 4.60 | 4.60 |
| 400.48 | 4.32 | 4.32 |
| 471.61 | 4.60 | 4.60 |
| 511.67 | 5.38 | 5.38 |
| 414.51 | 4.54 | 4.54 |
| 472.59 | 4.63 | 4.63 |
| 456.55 | 4.61 | 4.61 |
| 400.53 | 5.02 | 5.02 |
| 458.56 | 4.46 | 4.46 |
| 497.64 | 4.99 | 4.99 |
| 457.58 | 4.42 | 4.42 |
| 442.56 | 4.96 | 4.96 |
| 386.46 | 3.98 | 3.98 |
| 428.54 | 4.95 | 4.95 |
| 443.55 | 4.03 | 4.03 |
| 442.56 | 5.28 | 5.28 |
| 499.66 | 5.38 | 5.38 |
| 539.60 | 5.53 | 5.53 |
| 485.63 | 4.99 | 4.99 |
| 457.58 | 4.21 | 4.21 |
| 471.61 | 4.60 | 4.60 |
| 471.61 | 4.60 | 4.60 |
| 428.54 | 4.89 | 4.89 |
| 428.54 | 4.89 | 4.89 |
| 471.61 | 4.60 | 4.60 |