Basic Information
ID: ALA685651
Type: Functional
Description: In vivo ability to inhibit bronchospasm induced by intravenous doses of histamine on the artificially respired, anesthetized guinea pig
Format: BAO_0000218
Organism: Oryctolagus cuniculus
Target: Phosphodiesterase 4(ALA2093863)
Document: ALA1126116
In vivo ability to inhibit bronchospasm induced by intravenous doses of histamine on the artificially respired, anesthetized guinea pig: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA685651
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 271.12 | 1.68 | 1.68 |
| 285.14 | 2.07 | 2.07 |
| 257.09 | 1.03 | 1.03 |
| 252.07 | 1.41 | 1.41 |
| 258.07 | 0.99 | 0.99 |
| 204.23 | 0.57 | 0.57 |
| 162.20 | 1.16 | 1.16 |
| 242.08 | 1.89 | 1.89 |
| 241.09 | 1.92 | 1.92 |
| 149.15 | 0.74 | 0.74 |
| 213.04 | 1.07 | 1.07 |
| 228.05 | 1.50 | 1.50 |
| 148.17 | 0.77 | 0.77 |
| 163.18 | 1.13 | 1.13 |
| 242.08 | 1.89 | 1.89 |
| 227.06 | 1.53 | 1.53 |
| 228.05 | 1.50 | 1.50 |
| 134.14 | 0.31 | 0.31 |
| 241.09 | 1.92 | 1.92 |
| 227.06 | 1.53 | 1.53 |
| 213.04 | 1.07 | 1.07 |
| 283.13 | 1.33 | 1.33 |
| 180.17 | -1.04 | -1.04 |