Basic Information
ID: ALA686676
Type: Binding
Description: Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)
Activity Charts
Bioactivity
Activity Types for Assay ALA686676
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 238.29 | 3.12 | 3.12 |
| 263.34 | 4.30 | 4.30 |
| 278.36 | 3.55 | 3.55 |
| 266.34 | 3.69 | 3.69 |
| 310.35 | 3.30 | 3.30 |
| 228.23 | 2.65 | 2.65 |
| 266.34 | 3.69 | 3.69 |
| 273.38 | 3.96 | 3.96 |
| 252.32 | 3.43 | 3.43 |
| 306.18 | 4.00 | 4.00 |
| 306.18 | 4.00 | 4.00 |
| 245.67 | 2.56 | 2.56 |
| 259.70 | 2.57 | 2.57 |
| 239.27 | 3.33 | 3.33 |
| 225.25 | 3.08 | 3.08 |
| 265.27 | 2.88 | 2.88 |
| 386.29 | 5.25 | 5.25 |
| 355.87 | 5.79 | 5.79 |
| 244.68 | 3.16 | 3.16 |
| 224.26 | 2.82 | 2.82 |
| 210.24 | 2.51 | 2.51 |
| 318.42 | 4.56 | 4.56 |
| 341.84 | 5.14 | 5.14 |
| 256.28 | 3.26 | 3.26 |
| 420.73 | 5.90 | 5.90 |
| 307.39 | 4.49 | 4.49 |
| 321.42 | 5.13 | 5.13 |
| 296.33 | 2.83 | 2.83 |
| 306.37 | 3.02 | 3.02 |
| 296.33 | 2.99 | 2.99 |
| 310.35 | 2.92 | 2.92 |
| 211.22 | 2.77 | 2.77 |
| 255.34 | 3.80 | 3.80 |
| 287.41 | 4.27 | 4.27 |
| 238.29 | 3.12 | 3.12 |
| 224.26 | 2.52 | 2.52 |
| 255.23 | 2.42 | 2.42 |
| 314.18 | 3.97 | 3.97 |
| 252.32 | 3.43 | 3.43 |
| 300.16 | 3.94 | 3.94 |
| 251.29 | 3.19 | 3.19 |
| 304.39 | 4.17 | 4.17 |
| 290.37 | 3.78 | 3.78 |
| 237.26 | 2.88 | 2.88 |
| 385.26 | 3.78 | 3.78 |
| 340.81 | 3.67 | 3.67 |
| 347.42 | 2.77 | 2.77 |
| 282.32 | 3.38 | 3.38 |
| 320.39 | 3.32 | 3.32 |
| 412.29 | 3.22 | 3.22 |
| 333.39 | 2.46 | 2.46 |
| 278.36 | 3.27 | 3.27 |
| 349.47 | 5.48 | 5.48 |
| 264.33 | 3.25 | 3.25 |