Basic Information
ID: ALA701321
Type: Functional
Description: Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA701321
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 237.28 | 2.13 | 2.13 |
| 318.30 | 3.11 | 3.11 |
| 236.30 | 2.73 | 2.73 |
| 270.74 | 3.39 | 3.39 |
| 270.74 | 3.39 | 3.39 |
| 290.25 | 2.33 | 2.33 |
| 304.28 | 2.72 | 2.72 |
| 144.17 | 0.56 | 0.56 |
| 266.32 | 2.74 | 2.74 |
| 260.32 | 2.41 | 2.41 |
| 194.19 | 0.79 | 0.79 |
| 194.19 | 0.79 | 0.79 |
| 312.37 | 3.74 | 3.74 |
| 298.34 | 3.35 | 3.35 |
| 286.33 | 3.19 | 3.19 |
| 314.32 | 3.13 | 3.13 |
| 210.23 | 1.54 | 1.54 |
| 259.10 | 2.28 | 2.28 |
| 194.23 | 1.83 | 1.83 |
| 180.21 | 1.52 | 1.52 |
| 296.33 | 2.99 | 2.99 |
| 186.24 | 1.58 | 1.58 |
| 200.26 | 1.89 | 1.89 |
| 276.36 | 3.17 | 3.17 |
| 268.36 | 3.31 | 3.31 |
| 288.37 | 3.75 | 3.75 |
| 196.21 | 1.15 | 1.15 |
| 210.23 | 1.54 | 1.54 |
| 196.21 | 1.15 | 1.15 |
| 263.32 | 2.64 | 2.64 |
| 262.33 | 3.25 | 3.25 |
| 198.25 | 1.53 | 1.53 |
| 186.24 | 1.33 | 1.33 |
| 212.27 | 1.92 | 1.92 |
| 258.28 | 2.73 | 2.73 |
| 200.26 | 1.89 | 1.89 |
| 214.29 | 2.20 | 2.20 |
| 256.26 | 2.86 | 2.86 |
| 196.21 | 1.45 | 1.45 |
| 186.24 | 1.58 | 1.58 |
| 317.35 | 1.97 | 1.97 |
| 196.21 | 1.45 | 1.45 |
| 242.32 | 2.79 | 2.79 |
| 210.23 | 1.76 | 1.76 |
| 196.21 | 1.37 | 1.37 |
| 254.67 | 2.92 | 2.92 |
| 182.18 | 1.06 | 1.06 |
| 237.28 | 2.13 | 2.13 |
| 306.37 | 4.34 | 4.34 |
| 272.30 | 3.31 | 3.31 |
| 170.17 | 0.86 | 0.86 |
| 290.32 | 2.83 | 2.83 |
| 228.25 | 1.65 | 1.65 |
| 247.25 | 2.17 | 2.17 |
| 246.27 | 2.78 | 2.78 |
| 184.19 | 1.42 | 1.42 |
| 184.19 | 1.42 | 1.42 |
| 226.28 | 2.45 | 2.45 |
| 288.35 | 3.70 | 3.70 |
| 232.24 | 2.22 | 2.22 |
| 282.30 | 2.60 | 2.60 |
| 270.74 | 3.39 | 3.39 |
| 219.24 | 2.00 | 2.00 |
| 172.23 | 1.34 | 1.34 |
| 158.20 | 0.95 | 0.95 |
| 330.43 | 4.32 | 4.32 |
| 156.14 | 0.55 | 0.55 |
| 170.17 | 1.11 | 1.11 |
| 170.17 | 1.11 | 1.11 |
| 306.29 | 3.38 | 3.38 |
| 323.28 | 2.33 | 2.33 |
| 130.15 | 0.17 | 0.17 |
| 300.36 | 3.66 | 3.66 |
| 144.17 | 0.55 | 0.55 |
| 280.37 | 3.25 | 3.25 |
| 198.22 | 1.73 | 1.73 |
| 156.14 | 0.55 | 0.55 |
| 318.37 | 2.99 | 2.99 |
| 324.28 | 3.68 | 3.68 |
| 170.17 | 0.86 | 0.86 |
| 184.19 | 1.17 | 1.17 |
| 337.31 | 2.72 | 2.72 |
| 318.30 | 2.97 | 2.97 |
| 318.30 | 2.97 | 2.97 |