Basic Information
ID: ALA705534
Type: Functional
Description: Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA705534
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 412.56 | 4.38 | 4.38 |
| 422.53 | 4.22 | 4.22 |
| 426.51 | 3.02 | 3.02 |
| 351.45 | 3.85 | 3.85 |
| 436.55 | 4.56 | 4.56 |
| 406.53 | 4.00 | 4.00 |
| 456.59 | 4.66 | 4.66 |
| 486.61 | 5.27 | 5.27 |
| 434.54 | 4.14 | 4.14 |
| 426.49 | 4.05 | 4.05 |
| 423.51 | 3.61 | 3.61 |
| 442.56 | 4.74 | 4.74 |
| 470.61 | 5.05 | 5.05 |
| 438.57 | 4.83 | 4.83 |
| 406.53 | 4.00 | 4.00 |
| 436.55 | 4.61 | 4.61 |
| 458.56 | 5.55 | 5.55 |
| 420.55 | 4.39 | 4.39 |
| 454.57 | 4.07 | 4.07 |
| 440.52 | 4.36 | 4.36 |
| 396.49 | 3.66 | 3.66 |
| 337.42 | 3.51 | 3.51 |
| 337.42 | 3.51 | 3.51 |
| 341.84 | 4.15 | 4.15 |
| 336.44 | 3.54 | 3.54 |
| 408.54 | 4.22 | 4.22 |
| 456.59 | 4.66 | 4.66 |
| 442.56 | 4.74 | 4.74 |
| 394.51 | 3.83 | 3.83 |
| 423.51 | 4.64 | 4.64 |
| 440.54 | 3.68 | 3.68 |
| 462.59 | 5.12 | 5.12 |
| 307.39 | 3.50 | 3.50 |
| 458.56 | 5.55 | 5.55 |
| 382.46 | 3.40 | 3.40 |
| 462.59 | 5.12 | 5.12 |
| 440.54 | 3.68 | 3.68 |
| 456.97 | 4.87 | 4.87 |
| 442.94 | 4.57 | 4.57 |
| 454.57 | 4.07 | 4.07 |
| 380.49 | 3.44 | 3.44 |
| 338.45 | 3.09 | 3.09 |
| 351.45 | 3.90 | 3.90 |
| 500.64 | 5.66 | 5.66 |
| 456.97 | 4.87 | 4.87 |
| 470.61 | 5.05 | 5.05 |
| 353.42 | 3.09 | 3.09 |
| 297.40 | 3.86 | 3.86 |
| 424.54 | 4.44 | 4.44 |
| 337.42 | 3.51 | 3.51 |
| 436.55 | 4.61 | 4.61 |
| 436.55 | 4.56 | 4.56 |
| 472.58 | 5.23 | 5.23 |
| 435.57 | 4.13 | 4.13 |
| 380.49 | 3.35 | 3.35 |
| 521.46 | 5.50 | 5.50 |
| 247.34 | 3.01 | 3.01 |
| 373.47 | 3.05 | 3.05 |
| 472.58 | 5.23 | 5.23 |
| 426.51 | 3.02 | 3.02 |
| 438.57 | 4.83 | 4.83 |
| 424.54 | 4.44 | 4.44 |
| 521.46 | 5.50 | 5.50 |
| 521.46 | 5.50 | 5.50 |