Basic Information
ID: ALA711316
Type: Binding
Description: Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)
Activity Charts
Bioactivity
Activity Types for Assay ALA711316
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.50 | 4.16 | 4.16 |
| 351.38 | 0.63 | 0.63 |
| 455.92 | 3.78 | 3.78 |
| 362.41 | 1.32 | 1.32 |
| 362.41 | 1.32 | 1.32 |
| 439.46 | 3.26 | 3.26 |
| 439.46 | 3.26 | 3.26 |
| 463.52 | 3.58 | 3.58 |
| 401.44 | 1.80 | 1.80 |
| 456.52 | 1.63 | 1.63 |
| 366.40 | 0.05 | 0.05 |
| 352.37 | 0.04 | 0.04 |
| 471.56 | 2.30 | 2.30 |
| 375.40 | 1.46 | 1.46 |
| 467.50 | 2.27 | 2.27 |
| 477.54 | 2.66 | 2.66 |
| 436.49 | 2.54 | 2.54 |
| 426.47 | 1.16 | 1.16 |
| 497.53 | 2.93 | 2.93 |
| 548.60 | 2.09 | 2.09 |
| 378.41 | 1.02 | 1.02 |
| 405.46 | 2.02 | 2.02 |
| 422.46 | 3.21 | 3.21 |
| 419.46 | 1.88 | 1.88 |
| 481.53 | 3.06 | 3.06 |
| 548.62 | 2.17 | 2.17 |
| 377.42 | 0.90 | 0.90 |
| 448.50 | 0.60 | 0.60 |
| 496.20 | 2.89 | 2.89 |
| 462.58 | 2.55 | 2.55 |
| 391.40 | 1.17 | 1.17 |
| 484.46 | 3.17 | 3.17 |
| 484.46 | 3.17 | 3.17 |
| 461.50 | 0.75 | 0.75 |
| 469.49 | 3.17 | 3.17 |
| 408.48 | 2.97 | 2.97 |
| 478.57 | 2.20 | 2.20 |
| 666.75 | 2.71 | 2.71 |
| 464.54 | 3.19 | 3.19 |
| 450.47 | 1.85 | 1.85 |
| 435.46 | 3.36 | 3.36 |
| 419.46 | 1.88 | 1.88 |
| 360.44 | 1.49 | 1.49 |
| 404.49 | 2.49 | 2.49 |
| 417.49 | 1.14 | 1.14 |
| 389.43 | 1.27 | 1.27 |
| 475.57 | 2.70 | 2.70 |
| 442.92 | 3.63 | 3.63 |
| 361.42 | 0.89 | 0.89 |
| 332.38 | 1.31 | 1.31 |
| 424.48 | 3.10 | 3.10 |
| 456.50 | 3.03 | 3.03 |
| 480.72 | 5.73 | 5.73 |
| 346.41 | 1.45 | 1.45 |
| 382.44 | 2.46 | 2.46 |
| 462.48 | 3.12 | 3.12 |
| 371.41 | 2.07 | 2.07 |
| 425.51 | 2.53 | 2.53 |
| 428.49 | 2.58 | 2.58 |
| 480.54 | 3.31 | 3.31 |
| 412.43 | 1.04 | 1.04 |
| 471.92 | 3.48 | 3.48 |
| 447.51 | 3.63 | 3.63 |
| 441.48 | 2.70 | 2.70 |
| 500.92 | 3.68 | 3.68 |
| 390.42 | 1.05 | 1.05 |
| 448.50 | 2.85 | 2.85 |
| 400.38 | 2.33 | 2.33 |
| 467.55 | 3.17 | 3.17 |
| 462.48 | 3.26 | 3.26 |
| 454.48 | 2.84 | 2.84 |
| 499.48 | 1.12 | 1.12 |
| 449.48 | 2.69 | 2.69 |
| 437.47 | 3.25 | 3.25 |
| 429.52 | 2.57 | 2.57 |
| 449.53 | 3.31 | 3.31 |
| 494.53 | 2.61 | 2.61 |
| 451.55 | 3.04 | 3.04 |
| 418.45 | 2.17 | 2.17 |
| 421.47 | 3.12 | 3.12 |
| 453.54 | 3.61 | 3.61 |
| 470.93 | 3.36 | 3.36 |
| 500.92 | 3.68 | 3.68 |
| 554.60 | 4.61 | 4.61 |
| 471.92 | 3.90 | 3.90 |
| 541.60 | 4.46 | 4.46 |
| 489.47 | 4.14 | 4.14 |
| 407.40 | 1.22 | 1.22 |
| 424.27 | 2.22 | 2.22 |
| 455.92 | 3.78 | 3.78 |