Basic Information
ID: ALA746892
Type: Functional
Description: In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibition
Format: BAO_0000019
Target: Sodium/hydrogen exchanger 1(ALA2577)
Document: ALA1135437
In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibition: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA746892
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.35 | 0.63 | 0.63 |
| 560.51 | 3.47 | 3.47 |
| 517.61 | 2.55 | 2.55 |
| 298.35 | 1.88 | 1.88 |
| 560.51 | 3.47 | 3.47 |
| 536.03 | 2.45 | 2.45 |
| 517.61 | 2.55 | 2.55 |
| 520.03 | 2.75 | 2.75 |
| 520.03 | 2.75 | 2.75 |
| 401.73 | 2.15 | 2.15 |
| 400.74 | 2.75 | 2.75 |
| 372.33 | 2.16 | 2.16 |
| 406.77 | 2.81 | 2.81 |
| 365.26 | 3.15 | 3.15 |
| 441.22 | 3.47 | 3.47 |
| 372.32 | 2.16 | 2.16 |
| 402.28 | 2.38 | 2.38 |
| 400.74 | 2.75 | 2.75 |
| 366.30 | 2.10 | 2.10 |
| 316.79 | 2.40 | 2.40 |
| 396.32 | 2.11 | 2.11 |
| 400.74 | 2.75 | 2.75 |
| 399.71 | 3.15 | 3.15 |
| 441.22 | 3.47 | 3.47 |
| 435.19 | 3.40 | 3.40 |
| 398.31 | 2.55 | 2.55 |
| 445.19 | 2.86 | 2.86 |
| 352.27 | 2.00 | 2.00 |
| 366.30 | 2.10 | 2.10 |
| 340.26 | 1.93 | 1.93 |
| 414.31 | 2.25 | 2.25 |
| 401.73 | 2.15 | 2.15 |
| 418.73 | 2.89 | 2.89 |
| 435.19 | 3.40 | 3.40 |
| 380.32 | 2.41 | 2.41 |
| 353.25 | 2.95 | 2.95 |
| 406.77 | 2.81 | 2.81 |
| 314.78 | 2.40 | 2.40 |
| 356.26 | 1.69 | 1.69 |
| 435.19 | 3.40 | 3.40 |
| 380.32 | 2.41 | 2.41 |
| 384.29 | 2.24 | 2.24 |
| 369.32 | 3.42 | 3.42 |
| 368.31 | 2.34 | 2.34 |
| 389.72 | 2.08 | 2.08 |