Basic Information
ID: ALA751606
Type: Binding
Description: Inhibitory activity against P-glycoprotein expressed in murine mammary carcinoma (EMT6/AR1.0 cell line) in single-dose potentiation assay
Activity Charts
Bioactivity
Activity Types for Assay ALA751606
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 582.57 | 3.40 | 3.40 |
| 537.57 | 3.49 | 3.49 |
| 447.49 | 3.34 | 3.34 |
| 465.51 | 2.57 | 2.57 |
| 442.90 | 3.81 | 3.81 |
| 437.50 | 3.20 | 3.20 |
| 451.53 | 3.23 | 3.23 |
| 468.46 | 3.67 | 3.67 |
| 408.46 | 3.16 | 3.16 |
| 418.45 | 3.58 | 3.58 |
| 438.44 | 3.66 | 3.66 |
| 433.47 | 3.03 | 3.03 |
| 542.03 | 3.65 | 3.65 |
| 436.47 | 2.85 | 2.85 |
| 438.44 | 3.66 | 3.66 |
| 524.53 | 3.70 | 3.70 |
| 550.61 | 2.09 | 2.09 |
| 408.46 | 3.16 | 3.16 |
| 486.95 | 3.96 | 3.96 |
| 549.63 | 2.70 | 2.70 |
| 510.51 | 2.47 | 2.47 |
| 442.90 | 3.81 | 3.81 |
| 422.48 | 3.47 | 3.47 |
| 451.48 | 3.54 | 3.54 |
| 451.48 | 2.26 | 2.26 |
| 466.54 | 3.95 | 3.95 |
| 484.55 | 4.67 | 4.67 |
| 423.47 | 3.76 | 3.76 |
| 438.48 | 3.17 | 3.17 |
| 493.56 | 3.00 | 3.00 |
| 514.58 | 4.17 | 4.17 |
| 529.55 | 4.58 | 4.58 |
| 529.55 | 4.58 | 4.58 |
| 508.53 | 3.33 | 3.33 |
| 450.49 | 2.86 | 2.86 |
| 427.89 | 4.36 | 4.36 |
| 527.58 | 3.77 | 3.77 |
| 452.47 | 3.67 | 3.67 |
| 542.59 | 5.38 | 5.38 |