Basic Information
ID: ALA753371
Type: Functional
Description: Dose of drug needed to provide a percentage increase in life span of tumor-bearing mice in vivo of 50% compared to untreated controls after inoculation of 10e6 P388 leukemia cells; h=ILS of >50% could not be obtained at any dose level
Organism: Mus musculus
Cell type: P388
Activity Charts
Bioactivity
Activity Types for Assay ALA753371
D50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.38 | 5.85 | 5.85 |
| 471.48 | 5.35 | 5.35 |
| 427.83 | 6.60 | 6.60 |
| 423.41 | 5.95 | 5.95 |
| 420.49 | 3.86 | 3.86 |
| 408.44 | 4.41 | 4.41 |
| 441.53 | 3.91 | 3.91 |
| 442.34 | 5.27 | 5.27 |
| 393.47 | 4.51 | 4.51 |
| 377.47 | 4.81 | 4.81 |
| 407.50 | 4.82 | 4.82 |
| 437.44 | 6.26 | 6.26 |
| 407.41 | 6.25 | 6.25 |
| 397.89 | 5.16 | 5.16 |