Basic Information
ID: ALA755827
Type: Functional
Description: Inhibition of P-glycoprotein, human L-MDR1 expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay
Cell type: LLC-PK1
Activity Charts
Bioactivity
Activity Types for Assay ALA755827
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 252.35 | 0.60 | 0.60 |
| 285.34 | 1.20 | 1.20 |
| 416.13 | 6.45 | 6.45 |
| 733.94 | 1.79 | 1.79 |
| 344.85 | 5.38 | 5.38 |
| 399.44 | 2.87 | 2.87 |
| 670.86 | 3.09 | 3.09 |
| 567.80 | 4.75 | 4.75 |
| 471.69 | 6.45 | 6.45 |
| 325.77 | 4.32 | 4.32 |
| 458.58 | 5.35 | 5.35 |
| 588.56 | 1.34 | 1.34 |
| 810.99 | 3.99 | 3.99 |
| 495.64 | 5.27 | 5.27 |
| 1202.63 | ||
| 645.80 | 1.11 | 1.11 |
| 720.96 | 5.91 | 5.91 |
| 705.65 | 5.58 | 5.58 |
| 324.42 | 3.17 | 3.17 |
| 531.44 | 4.21 | 4.21 |
| 461.56 | 5.86 | 5.86 |
| 392.47 | 1.90 | 1.90 |
| 362.47 | 1.78 | 1.78 |
| 479.53 | 3.68 | 3.68 |
| 780.95 | 2.22 | 2.22 |
| 1736.18 | ||
| 314.41 | 1.46 | 1.46 |