Basic Information
ID: ALA756011
Type: Binding
Description: Binding affinity for nicotinic acetylcholine receptor alpha4-beta2 was evaluated by its ability to inhibit [3H]NIC binding to rat brain membranes
Organism: Rattus norvegicus
Tissue: Brain
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA756011
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 162.24 | 1.85 | 1.85 |
| 472.31 | 4.31 | 4.31 |
| 500.36 | 5.09 | 5.09 |
| 402.36 | 4.10 | 4.10 |
| 514.39 | 5.48 | 5.48 |
| 580.34 | 4.70 | 4.70 |
| 552.28 | 3.92 | 3.92 |
| 524.23 | 3.14 | 3.14 |
| 430.42 | 4.88 | 4.88 |
| 662.44 | 4.06 | 4.06 |
| 496.17 | 2.52 | 2.52 |
| 572.43 | 6.78 | 6.78 |
| 586.46 | 7.17 | 7.17 |
| 652.40 | 6.39 | 6.39 |
| 652.60 | 6.40 | 6.40 |
| 704.52 | 5.23 | 5.23 |
| 444.26 | 3.69 | 3.69 |
| 486.34 | 4.86 | 4.86 |
| 586.46 | 7.17 | 7.17 |
| 624.35 | 5.61 | 5.61 |
| 596.29 | 4.83 | 4.83 |
| 544.38 | 6.00 | 6.00 |
| 572.43 | 6.78 | 6.78 |
| 652.40 | 6.39 | 6.39 |
| 718.55 | 5.62 | 5.62 |
| 418.30 | 3.52 | 3.52 |
| 638.58 | 6.01 | 6.01 |
| 544.38 | 6.00 | 6.00 |
| 273.29 | 1.96 | 1.96 |
| 624.35 | 5.61 | 5.61 |
| 596.29 | 4.83 | 4.83 |
| 472.31 | 4.47 | 4.47 |
| 524.23 | 3.30 | 3.30 |
| 690.50 | 4.84 | 4.84 |
| 482.15 | 2.13 | 2.13 |
| 552.28 | 4.08 | 4.08 |
| 682.81 | 2.04 | 2.04 |
| 645.20 | 6.70 | 6.70 |