ID: ALA757136
Type: Binding
Description: Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.
Cell type: U-937
Bioactivity
Activity Types for Assay ALA757136
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
275.35 | 2.62 | 2.62 |
412.45 | 2.59 | 2.59 |
397.44 | 2.16 | 2.16 |
396.45 | 2.89 | 2.89 |
425.49 | 3.50 | 3.50 |
465.52 | 2.55 | 2.55 |
462.51 | 3.74 | 3.74 |
446.51 | 4.04 | 4.04 |
432.48 | 3.73 | 3.73 |
479.37 | 4.38 | 4.38 |
477.48 | 3.64 | 3.64 |
462.51 | 3.74 | 3.74 |
382.42 | 2.58 | 2.58 |
411.46 | 2.35 | 2.35 |
412.45 | 1.74 | 1.74 |
534.45 | 4.67 | 4.67 |
426.48 | 2.77 | 2.77 |
451.53 | 3.18 | 3.18 |
447.50 | 3.31 | 3.31 |
512.57 | 3.51 | 3.51 |
465.34 | 4.19 | 4.19 |
439.48 | 2.54 | 2.54 |
497.56 | 3.92 | 3.92 |
466.33 | 3.47 | 3.47 |
451.31 | 3.88 | 3.88 |
522.39 | 4.03 | 4.03 |
480.36 | 3.65 | 3.65 |
520.60 | 2.84 | 2.84 |
466.51 | 1.82 | 1.82 |
508.41 | 4.14 | 4.14 |
397.44 | 2.16 | 2.16 |
397.44 | 2.16 | 2.16 |
427.42 | 2.49 | 2.49 |
382.42 | 2.58 | 2.58 |
481.52 | 2.25 | 2.25 |
447.50 | 3.31 | 3.31 |
343.42 | 4.05 | 4.05 |