Basic Information
ID: ALA763870
Type: Binding
Description: Inhibition of human Prostaglandin G/H synthase 2
Activity Charts
Bioactivity
Activity Types for Assay ALA763870
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 316.40 | 4.32 | 4.32 |
| 384.35 | 4.10 | 4.10 |
| 381.38 | 3.51 | 3.51 |
| 343.42 | 3.96 | 3.96 |
| 338.39 | 2.37 | 2.37 |
| 344.35 | 2.09 | 2.09 |
| 427.40 | 3.22 | 3.22 |
| 439.48 | 4.24 | 4.24 |
| 349.36 | 3.12 | 3.12 |
| 367.35 | 3.21 | 3.21 |
| 372.84 | 2.91 | 2.91 |
| 409.39 | 3.14 | 3.14 |
| 331.37 | 2.66 | 2.66 |
| 425.39 | 3.24 | 3.24 |
| 407.42 | 3.69 | 3.69 |
| 363.39 | 3.43 | 3.43 |
| 371.38 | 3.50 | 3.50 |
| 448.28 | 4.44 | 4.44 |
| 430.84 | 3.90 | 3.90 |
| 401.80 | 3.86 | 3.86 |
| 383.81 | 3.78 | 3.78 |
| 381.38 | 3.51 | 3.51 |
| 395.41 | 3.82 | 3.82 |
| 352.74 | 5.22 | 5.22 |
| 436.24 | 4.51 | 4.51 |
| 398.27 | 2.99 | 2.99 |
| 347.83 | 3.15 | 3.15 |
| 363.83 | 2.33 | 2.33 |
| 445.85 | 4.18 | 4.18 |
| 357.16 | 5.86 | 5.86 |
| 415.37 | 3.41 | 3.41 |
| 396.39 | 3.25 | 3.25 |
| 397.38 | 3.27 | 3.27 |
| 348.32 | 4.58 | 4.58 |
| 413.83 | 3.79 | 3.79 |
| 412.70 | 3.60 | 3.60 |
| 425.43 | 3.78 | 3.78 |
| 411.40 | 3.52 | 3.52 |
| 407.37 | 3.95 | 3.95 |
| 429.85 | 4.42 | 4.42 |
| 415.82 | 4.17 | 4.17 |
| 423.44 | 4.42 | 4.42 |
| 436.24 | 4.51 | 4.51 |
| 410.42 | 3.27 | 3.27 |
| 397.38 | 3.21 | 3.21 |
| 411.41 | 3.60 | 3.60 |
| 397.38 | 3.21 | 3.21 |
| 385.34 | 3.34 | 3.34 |
| 385.34 | 3.34 | 3.34 |
| 333.80 | 2.84 | 2.84 |
| 379.39 | 3.13 | 3.13 |
| 436.24 | 4.51 | 4.51 |
| 397.38 | 3.21 | 3.21 |
| 412.35 | 3.11 | 3.11 |
| 382.37 | 2.79 | 2.79 |
| 397.38 | 3.21 | 3.21 |
| 452.28 | 4.03 | 4.03 |
| 411.27 | 2.59 | 2.59 |
| 385.34 | 3.34 | 3.34 |
| 407.83 | 3.92 | 3.92 |
| 342.36 | 2.20 | 2.20 |
| 401.80 | 3.86 | 3.86 |
| 381.38 | 3.51 | 3.51 |
| 426.28 | 3.28 | 3.28 |
| 401.46 | 4.06 | 4.06 |
| 363.84 | 4.65 | 4.65 |
| 408.29 | 4.76 | 4.76 |
| 427.42 | 4.59 | 4.59 |
| 354.41 | 3.87 | 3.87 |
| 433.50 | 5.23 | 5.23 |
| 329.40 | 4.00 | 4.00 |
| 359.42 | 3.49 | 3.49 |
| 357.41 | 3.81 | 3.81 |
| 371.43 | 4.20 | 4.20 |
| 425.40 | 4.74 | 4.74 |
| 315.37 | 3.69 | 3.69 |
| 353.44 | 4.06 | 4.06 |
| 325.43 | 4.16 | 4.16 |
| 379.40 | 4.88 | 4.88 |
| 311.41 | 3.86 | 3.86 |
| 316.36 | 2.93 | 2.93 |
| 347.39 | 4.13 | 4.13 |
| 411.42 | 5.10 | 5.10 |
| 432.37 | 4.25 | 4.25 |
| 399.37 | 3.65 | 3.65 |
| 415.82 | 4.17 | 4.17 |
| 465.28 | 5.28 | 5.28 |
| 476.27 | 3.98 | 3.98 |
| 431.82 | 3.87 | 3.87 |
| 415.37 | 3.35 | 3.35 |
| 398.38 | 4.41 | 4.41 |
| 394.42 | 4.58 | 4.58 |
| 402.34 | 4.24 | 4.24 |
| 346.84 | 3.90 | 3.90 |
| 414.84 | 4.92 | 4.92 |
| 366.36 | 3.96 | 3.96 |
| 430.83 | 4.62 | 4.62 |
| 398.38 | 4.41 | 4.41 |
| 414.84 | 4.92 | 4.92 |
| 429.85 | 4.66 | 4.66 |
| 478.32 | 5.33 | 5.33 |
| 396.39 | 3.97 | 3.97 |
| 398.38 | 4.41 | 4.41 |
| 385.34 | 3.34 | 3.34 |
| 427.42 | 4.17 | 4.17 |
| 443.88 | 4.68 | 4.68 |
| 381.38 | 3.51 | 3.51 |
| 414.38 | 4.11 | 4.11 |
| 381.38 | 3.51 | 3.51 |
| 396.39 | 3.97 | 3.97 |
| 446.25 | 3.97 | 3.97 |
| 435.25 | 5.27 | 5.27 |
| 380.39 | 4.27 | 4.27 |
| 414.38 | 4.11 | 4.11 |
| 384.35 | 4.10 | 4.10 |
| 400.81 | 4.62 | 4.62 |
| 404.88 | 3.77 | 3.77 |
| 445.26 | 4.72 | 4.72 |
| 414.84 | 4.92 | 4.92 |
| 357.82 | 3.47 | 3.47 |
| 384.35 | 4.10 | 4.10 |
| 400.81 | 4.62 | 4.62 |
| 410.37 | 3.69 | 3.69 |
| 443.88 | 4.68 | 4.68 |
| 430.84 | 4.62 | 4.62 |
| 384.35 | 4.10 | 4.10 |
| 381.38 | 3.54 | 3.54 |
| 400.81 | 4.62 | 4.62 |
| 385.34 | 3.34 | 3.34 |
| 401.80 | 3.86 | 3.86 |
| 411.36 | 3.87 | 3.87 |
| 424.44 | 4.59 | 4.59 |
| 367.35 | 3.21 | 3.21 |
| 385.34 | 3.34 | 3.34 |
| 554.18 | 5.50 | 5.50 |
| 415.82 | 4.17 | 4.17 |
| 447.89 | 4.58 | 4.58 |
| 403.33 | 3.48 | 3.48 |
| 431.82 | 3.87 | 3.87 |
| 396.39 | 3.97 | 3.97 |
| 434.36 | 4.98 | 4.98 |
| 364.83 | 4.07 | 4.07 |
| 433.36 | 3.49 | 3.49 |
| 382.82 | 4.53 | 4.53 |
| 411.32 | 5.39 | 5.39 |
| 360.82 | 3.41 | 3.41 |
| 395.41 | 4.00 | 4.00 |
| 381.38 | 3.51 | 3.51 |
| 415.37 | 3.35 | 3.35 |
| 371.85 | 3.66 | 3.66 |
| 401.80 | 3.86 | 3.86 |
| 412.46 | 4.68 | 4.68 |
| 392.93 | 4.46 | 4.46 |
| 444.46 | 3.37 | 3.37 |
| 376.87 | 3.74 | 3.74 |
| 409.43 | 4.03 | 4.03 |
| 362.84 | 3.09 | 3.09 |
| 408.91 | 5.26 | 5.26 |
| 409.43 | 4.03 | 4.03 |
| 412.46 | 4.68 | 4.68 |
| 380.39 | 4.27 | 4.27 |
| 314.37 | 2.96 | 2.96 |
| 396.82 | 5.49 | 5.49 |
| 422.88 | 4.67 | 4.67 |
| 376.40 | 5.15 | 5.15 |
| 363.36 | 4.09 | 4.09 |
| 373.42 | 4.56 | 4.56 |
| 393.84 | 4.91 | 4.91 |
| 397.80 | 4.74 | 4.74 |
| 392.85 | 5.66 | 5.66 |
| 372.44 | 5.32 | 5.32 |
| 388.39 | 4.43 | 4.43 |
| 327.38 | 3.81 | 3.81 |
| 392.40 | 4.85 | 4.85 |
| 408.85 | 5.36 | 5.36 |
| 377.39 | 4.39 | 4.39 |
| 393.39 | 4.09 | 4.09 |
| 392.85 | 5.66 | 5.66 |
| 358.41 | 5.01 | 5.01 |
| 389.38 | 3.67 | 3.67 |
| 359.40 | 4.25 | 4.25 |
| 444.29 | 5.26 | 5.26 |
| 405.42 | 3.96 | 3.96 |
| 404.43 | 4.72 | 4.72 |
| 389.42 | 4.26 | 4.26 |
| 388.44 | 5.02 | 5.02 |
| 395.28 | 5.87 | 5.87 |
| 362.37 | 4.84 | 4.84 |
| 342.85 | 5.08 | 5.08 |
| 361.82 | 4.46 | 4.46 |
| 373.86 | 4.33 | 4.33 |
| 421.90 | 5.42 | 5.42 |
| 343.84 | 4.32 | 4.32 |
| 360.84 | 5.22 | 5.22 |
| 393.84 | 4.91 | 4.91 |
| 403.41 | 3.72 | 3.72 |
| 402.42 | 4.47 | 4.47 |
| 326.39 | 4.56 | 4.56 |
| 357.41 | 3.82 | 3.82 |
| 409.84 | 4.61 | 4.61 |
| 370.49 | 5.49 | 5.49 |
| 356.46 | 5.10 | 5.10 |
| 358.89 | 5.23 | 5.23 |
| 386.90 | 5.01 | 5.01 |
| 354.47 | 4.58 | 4.58 |
| 340.42 | 4.49 | 4.49 |
| 359.88 | 4.47 | 4.47 |
| 355.46 | 3.83 | 3.83 |
| 394.32 | 5.13 | 5.13 |
| 376.88 | 5.37 | 5.37 |
| 393.33 | 5.88 | 5.88 |
| 393.33 | 5.88 | 5.88 |
| 360.43 | 4.85 | 4.85 |
| 342.44 | 4.71 | 4.71 |
| 360.43 | 4.85 | 4.85 |
| 361.41 | 4.10 | 4.10 |
| 434.36 | 4.59 | 4.59 |
| 433.37 | 5.35 | 5.35 |
| 389.90 | 4.48 | 4.48 |
| 424.35 | 5.13 | 5.13 |
| 368.45 | 4.30 | 4.30 |
| 373.45 | 3.97 | 3.97 |
| 372.46 | 4.72 | 4.72 |
| 388.92 | 5.24 | 5.24 |
| 409.43 | 4.72 | 4.72 |
| 423.36 | 5.89 | 5.89 |
| 377.87 | 4.61 | 4.61 |
| 408.44 | 5.47 | 5.47 |
| 344.45 | 4.96 | 4.96 |
| 338.47 | 4.88 | 4.88 |
| 382.37 | 2.91 | 2.91 |
| 386.42 | 4.33 | 4.33 |
| 451.29 | 4.79 | 4.79 |
| 373.38 | 3.27 | 3.27 |
| 372.39 | 4.02 | 4.02 |
| 382.37 | 2.91 | 2.91 |
| 382.37 | 2.91 | 2.91 |
| 446.25 | 4.12 | 4.12 |
| 372.33 | 2.50 | 2.50 |
| 388.40 | 2.97 | 2.97 |
| 368.34 | 2.60 | 2.60 |
| 382.37 | 2.91 | 2.91 |
| 350.35 | 2.52 | 2.52 |
| 381.38 | 3.67 | 3.67 |
| 381.38 | 3.67 | 3.67 |
| 367.35 | 3.36 | 3.36 |
| 367.35 | 3.36 | 3.36 |
| 388.40 | 2.97 | 2.97 |
| 388.40 | 2.97 | 2.97 |
| 381.38 | 3.67 | 3.67 |
| 410.37 | 3.69 | 3.69 |
| 387.41 | 3.73 | 3.73 |
| 382.37 | 2.91 | 2.91 |
| 382.37 | 2.91 | 2.91 |
| 382.37 | 2.91 | 2.91 |
| 397.38 | 3.37 | 3.37 |
| 419.43 | 4.45 | 4.45 |
| 417.41 | 4.51 | 4.51 |
| 381.38 | 3.67 | 3.67 |
| 381.38 | 3.67 | 3.67 |
| 381.38 | 3.67 | 3.67 |
| 447.24 | 3.36 | 3.36 |
| 381.38 | 3.67 | 3.67 |
| 417.41 | 4.51 | 4.51 |
| 417.41 | 4.51 | 4.51 |
| 400.38 | 3.10 | 3.10 |
| 367.30 | 5.49 | 5.49 |
| 366.40 | 5.20 | 5.20 |
| 328.43 | 4.19 | 4.19 |
| 335.44 | 4.32 | 4.32 |
| 387.41 | 3.58 | 3.58 |
| 367.39 | 4.45 | 4.45 |
| 376.91 | 4.15 | 4.15 |
| 398.31 | 4.74 | 4.74 |
| 347.41 | 3.58 | 3.58 |
| 368.29 | 4.74 | 4.74 |
| 411.36 | 2.93 | 2.93 |
| 342.46 | 4.33 | 4.33 |
| 330.37 | 2.15 | 2.15 |
| 351.83 | 4.22 | 4.22 |
| 335.38 | 3.71 | 3.71 |
| 317.39 | 3.57 | 3.57 |
| 384.39 | 5.34 | 5.34 |
| 375.92 | 4.90 | 4.90 |
| 346.42 | 4.33 | 4.33 |
| 350.84 | 4.98 | 4.98 |
| 334.39 | 4.46 | 4.46 |
| 342.42 | 3.91 | 3.91 |
| 397.32 | 5.50 | 5.50 |
| 367.30 | 5.49 | 5.49 |
| 362.88 | 4.85 | 4.85 |
| 452.39 | 6.04 | 6.04 |
| 360.91 | 5.47 | 5.47 |
| 380.43 | 4.86 | 4.86 |
| 330.42 | 4.63 | 4.63 |
| 344.50 | 4.91 | 4.91 |
| 328.43 | 3.68 | 3.68 |
| 368.43 | 4.59 | 4.59 |
| 329.42 | 3.44 | 3.44 |
| 333.84 | 4.08 | 4.08 |
| 363.87 | 4.09 | 4.09 |
| 359.40 | 4.41 | 4.41 |
| 343.40 | 3.16 | 3.16 |
| 385.38 | 4.59 | 4.59 |