Basic Information
ID: ALA766247
Type: Binding
Description: Inhibition of Trypanosoma brucei phosphoglycerate kinase (PGK); inactive at 4 mM
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA766247
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.39 | 0.18 | 0.18 |
| 416.44 | -0.32 | -0.32 |
| 407.43 | 1.20 | 1.20 |
| 281.27 | -1.52 | -1.52 |
| 391.82 | 0.70 | 0.70 |
| 296.29 | -1.94 | -1.94 |
| 447.50 | 1.68 | 1.68 |
| 391.82 | 0.70 | 0.70 |
| 391.82 | 0.70 | 0.70 |
| 371.40 | 0.36 | 0.36 |
| 371.40 | 0.36 | 0.36 |
| 387.40 | 0.06 | 0.06 |
| 387.40 | 0.06 | 0.06 |
| 309.33 | -0.74 | -0.74 |
| 347.33 | -0.36 | -0.36 |
| 371.40 | 0.61 | 0.61 |
| 387.40 | -0.42 | -0.42 |
| 305.29 | -1.52 | -1.52 |
| 295.30 | -1.13 | -1.13 |
| 363.42 | 0.43 | 0.43 |
| 309.33 | -0.74 | -0.74 |
| 364.41 | -0.24 | -0.24 |
| 325.33 | -1.77 | -1.77 |
| 311.30 | -2.16 | -2.16 |
| 462.51 | 1.26 | 1.26 |
| 340.34 | -2.19 | -2.19 |
| 447.50 | 1.83 | 1.83 |
| 341.32 | -2.80 | -2.80 |
| 340.34 | -2.19 | -2.19 |
| 387.40 | -0.20 | -0.20 |
| 400.44 | -0.02 | -0.02 |
| 339.36 | -2.22 | -2.22 |
| 406.83 | 0.29 | 0.29 |
| 378.43 | 0.01 | 0.01 |
| 387.40 | -0.20 | -0.20 |
| 431.41 | -0.42 | -0.42 |
| 324.34 | -1.80 | -1.80 |
| 416.44 | -0.32 | -0.32 |
| 352.40 | -0.38 | -0.38 |
| 420.86 | 0.33 | 0.33 |
| 403.40 | -0.50 | -0.50 |
| 354.37 | -1.80 | -1.80 |
| 368.39 | -1.41 | -1.41 |
| 356.34 | -3.21 | -3.21 |
| 325.33 | -2.61 | -2.61 |
| 406.83 | 0.29 | 0.29 |
| 353.38 | -0.99 | -0.99 |
| 386.41 | -0.06 | -0.06 |
| 340.34 | -2.83 | -2.83 |
| 351.36 | -0.97 | -0.97 |
| 402.41 | -0.36 | -0.36 |
| 401.42 | 0.10 | 0.10 |
| 401.42 | 0.10 | 0.10 |
| 325.33 | -1.77 | -1.77 |
| 355.36 | -3.25 | -3.25 |
| 353.38 | -1.83 | -1.83 |
| 405.84 | 0.75 | 0.75 |
| 386.41 | -0.06 | -0.06 |
| 402.41 | -0.36 | -0.36 |
| 353.38 | -1.83 | -1.83 |
| 356.34 | -3.21 | -3.21 |
| 446.46 | -0.31 | -0.31 |
| 385.42 | 0.40 | 0.40 |
| 354.37 | -1.80 | -1.80 |
| 405.84 | 0.75 | 0.75 |
| 417.42 | -0.19 | -0.19 |
| 340.34 | -2.19 | -2.19 |
| 352.40 | -1.02 | -1.02 |
| 339.35 | -1.38 | -1.38 |
| 402.41 | -0.83 | -0.83 |
| 326.31 | -2.58 | -2.58 |
| 367.41 | -1.44 | -1.44 |
| 367.41 | -1.44 | -1.44 |
| 462.51 | 1.42 | 1.42 |
| 366.38 | -1.39 | -1.39 |
| 338.37 | -1.41 | -1.41 |
| 355.36 | -3.25 | -3.25 |
| 455.30 | 0.98 | 0.98 |
| 440.29 | 1.40 | 1.40 |
| 431.45 | 0.11 | 0.11 |
| 416.44 | -0.32 | -0.32 |
| 340.34 | -2.19 | -2.19 |
| 446.46 | -0.31 | -0.31 |
| 401.42 | 0.10 | 0.10 |
| 420.86 | 0.33 | 0.33 |
| 325.33 | -2.61 | -2.61 |
| 368.39 | -1.41 | -1.41 |
| 324.34 | -1.16 | -1.16 |
| 405.84 | 0.75 | 0.75 |
| 417.42 | -0.19 | -0.19 |
| 406.83 | 0.29 | 0.29 |
| 326.31 | -2.58 | -2.58 |
| 416.39 | 0.00 | 0.00 |
| 386.41 | -0.33 | -0.33 |
| 371.40 | 0.09 | 0.09 |
| 323.35 | -0.35 | -0.35 |
| 307.31 | -0.96 | -0.96 |
| 385.42 | 0.65 | 0.65 |
| 385.42 | 0.48 | 0.48 |