Basic Information
ID: ALA767670
Type: Functional
Description: 5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leukocytes
Activity Charts
Bioactivity
Activity Types for Assay ALA767670
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 226.23 | 2.23 | 2.23 |
| 374.39 | 3.61 | 3.61 |
| 360.37 | 3.52 | 3.52 |
| 284.27 | 1.86 | 1.86 |
| 340.38 | 3.42 | 3.42 |
| 340.38 | 3.12 | 3.12 |
| 313.31 | 1.67 | 1.67 |
| 388.38 | 3.25 | 3.25 |
| 389.41 | 3.29 | 3.29 |
| 403.43 | 3.41 | 3.41 |
| 355.39 | 2.82 | 2.82 |
| 403.39 | 2.93 | 2.93 |
| 327.34 | 2.06 | 2.06 |
| 299.28 | 1.28 | 1.28 |
| 223.27 | 1.91 | 1.91 |
| 374.35 | 3.16 | 3.16 |
| 326.35 | 3.06 | 3.06 |
| 388.42 | 4.03 | 4.03 |
| 312.32 | 2.34 | 2.34 |
| 341.36 | 2.45 | 2.45 |
| 326.35 | 2.73 | 2.73 |
| 298.29 | 1.95 | 1.95 |
| 375.38 | 2.94 | 2.94 |
| 389.41 | 3.06 | 3.06 |
| 341.36 | 2.48 | 2.48 |
| 313.31 | 1.84 | 1.84 |
| 374.39 | 3.64 | 3.64 |
| 298.29 | 2.42 | 2.42 |
| 326.35 | 3.03 | 3.03 |
| 312.32 | 2.64 | 2.64 |
| 298.29 | 2.25 | 2.25 |
| 355.39 | 2.79 | 2.79 |
| 340.38 | 3.15 | 3.15 |
| 312.32 | 2.51 | 2.51 |
| 327.34 | 2.18 | 2.18 |
| 369.42 | 3.18 | 3.18 |
| 341.36 | 2.40 | 2.40 |
| 327.34 | 2.01 | 2.01 |
| 313.31 | 1.62 | 1.62 |
| 388.42 | 3.73 | 3.73 |
| 354.40 | 3.51 | 3.51 |
| 402.45 | 4.12 | 4.12 |