Basic Information
ID: ALA768926
Type: Binding
Description: In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)
Activity Charts
Bioactivity
Activity Types for Assay ALA768926
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.52 | 7.24 | 7.24 |
| 510.59 | 8.63 | 8.63 |
| 539.59 | 8.01 | 8.01 |
| 376.46 | 7.06 | 7.06 |
| 506.27 | 6.71 | 6.71 |
| 557.48 | 8.36 | 8.36 |
| 505.37 | 5.95 | 5.95 |
| 604.48 | 8.20 | 8.20 |
| 750.49 | 9.52 | 9.52 |
| 671.59 | 8.76 | 8.76 |
| 491.39 | 6.30 | 6.30 |
| 571.47 | 8.00 | 8.00 |
| 471.42 | 8.29 | 8.29 |
| 477.45 | 6.03 | 6.03 |
| 538.64 | 8.82 | 8.82 |
| 390.44 | 6.70 | 6.70 |
| 438.53 | 6.06 | 6.06 |
| 430.50 | 5.99 | 5.99 |
| 530.26 | 7.75 | 7.75 |
| 543.54 | 8.08 | 8.08 |
| 453.42 | 6.47 | 6.47 |
| 372.46 | 6.23 | 6.23 |
| 550.32 | 9.06 | 9.06 |
| 356.47 | 6.74 | 6.74 |
| 414.50 | 6.50 | 6.50 |
| 644.32 | 8.74 | 8.74 |
| 467.36 | 6.75 | 6.75 |
| 400.47 | 6.57 | 6.57 |
| 358.51 | 7.28 | 7.28 |
| 456.32 | 6.83 | 6.83 |
| 424.52 | 6.94 | 6.94 |
| 608.35 | 8.81 | 8.81 |
| 486.50 | 5.94 | 5.94 |
| 529.46 | 8.05 | 8.05 |
| 342.44 | 6.82 | 6.82 |
| 528.54 | 6.16 | 6.16 |
| 662.81 | 10.64 | 10.64 |
| 701.33 | 9.60 | 9.60 |
| 567.69 | 8.87 | 8.87 |
| 553.66 | 8.48 | 8.48 |
| 799.54 | 9.70 | 9.70 |
| 676.44 | 10.68 | 10.68 |
| 524.62 | 8.43 | 8.43 |
| 490.60 | 8.18 | 8.18 |
| 502.61 | 8.48 | 8.48 |
| 648.39 | 9.90 | 9.90 |
| 409.32 | 6.99 | 6.99 |
| 425.32 | 6.48 | 6.48 |
| 346.43 | 5.72 | 5.72 |
| 330.43 | 6.23 | 6.23 |
| 781.52 | 9.87 | 9.87 |
| 813.56 | 9.79 | 9.79 |
| 543.54 | 8.08 | 8.08 |
| 658.73 | 8.83 | 8.83 |
| 570.69 | 7.46 | 7.46 |
| 662.81 | 10.64 | 10.64 |
| 665.61 | 9.74 | 9.74 |
| 635.58 | 9.73 | 9.73 |
| 635.58 | 9.73 | 9.73 |
| 592.69 | 8.00 | 8.00 |
| 644.75 | 9.19 | 9.19 |
| 621.62 | 7.44 | 7.44 |
| 604.68 | 8.15 | 8.15 |
| 611.21 | 7.99 | 7.99 |
| 553.17 | 8.23 | 8.23 |
| 635.61 | 7.08 | 7.08 |
| 557.51 | 8.83 | 8.83 |
| 616.74 | 8.98 | 8.98 |
| 586.71 | 8.97 | 8.97 |
| 570.71 | 9.36 | 9.36 |
| 556.68 | 8.97 | 8.97 |
| 576.63 | 7.53 | 7.53 |
| 576.63 | 7.53 | 7.53 |
| 560.63 | 7.82 | 7.82 |
| 526.66 | 8.96 | 8.96 |
| 560.63 | 7.82 | 7.82 |
| 603.51 | 9.19 | 9.19 |
| 524.62 | 8.43 | 8.43 |
| 524.62 | 8.43 | 8.43 |
| 619.58 | 9.66 | 9.66 |
| 600.74 | 8.92 | 8.92 |
| 600.74 | 8.92 | 8.92 |
| 510.59 | 8.56 | 8.56 |
| 648.39 | 9.76 | 9.76 |
| 540.68 | 8.90 | 8.90 |
| 538.64 | 8.82 | 8.82 |
| 682.41 | 9.96 | 9.96 |
| 630.74 | 10.11 | 10.11 |
| 569.61 | 8.34 | 8.34 |
| 620.34 | 9.12 | 9.12 |
| 552.67 | 9.05 | 9.05 |
| 592.74 | 10.09 | 10.09 |
| 698.48 | 10.43 | 10.43 |
| 646.81 | 10.58 | 10.58 |
| 651.23 | 11.22 | 11.22 |
| 712.50 | 10.82 | 10.82 |
| 506.67 | 8.65 | 8.65 |
| 492.64 | 8.78 | 8.78 |
| 538.60 | 8.07 | 8.07 |
| 540.62 | 7.92 | 7.92 |
| 558.67 | 9.04 | 9.04 |
| 570.71 | 8.91 | 8.91 |
| 448.52 | 7.21 | 7.21 |
| 612.75 | 9.41 | 9.41 |
| 572.68 | 8.31 | 8.31 |
| 518.68 | 8.36 | 8.36 |
| 490.62 | 7.75 | 7.75 |
| 524.62 | 8.43 | 8.43 |
| 525.60 | 7.83 | 7.83 |
| 538.64 | 8.74 | 8.74 |
| 541.67 | 8.30 | 8.30 |
| 547.70 | 8.36 | 8.36 |
| 542.61 | 8.57 | 8.57 |
| 607.66 | 7.88 | 7.88 |