Basic Information
ID: ALA769668
Type: Functional
Description: In vitro antimalarial activity relative to trimethoprim against Plasmodium falciparum Vl/S with quadruple DHFR mutant (N51I/C59R/S108N/I164L)
Organism: Plasmodium falciparum
Strain: V1/S
Activity Charts
Bioactivity
Activity Types for Assay ALA769668
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 306.37 | 2.81 | 2.81 |
| 426.52 | 4.70 | 4.70 |
| 454.53 | 3.63 | 3.63 |
| 440.55 | 4.95 | 4.95 |
| 412.49 | 4.39 | 4.39 |
| 468.55 | 4.02 | 4.02 |
| 440.50 | 3.24 | 3.24 |
| 396.45 | 2.84 | 2.84 |
| 350.42 | 3.21 | 3.21 |
| 426.47 | 2.85 | 2.85 |
| 336.40 | 2.82 | 2.82 |
| 336.40 | 2.82 | 2.82 |
| 306.37 | 2.81 | 2.81 |
| 304.35 | 1.57 | 1.57 |
| 318.38 | 1.82 | 1.82 |
| 350.42 | 3.13 | 3.13 |
| 364.45 | 3.38 | 3.38 |
| 292.34 | 3.02 | 3.02 |