ID: ALA780728
Type: Functional
Description: In vivo beta-adrenoceptor blocking potency measured by by blockade of the isoproterenol tachycardia response in rat
Bioactivity
Activity Types for Assay ALA780728
ED50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
334.44 | 1.43 | 1.43 |
332.83 | 2.32 | 2.32 |
265.36 | 0.66 | 0.66 |
358.44 | 1.69 | 1.69 |
355.44 | 1.63 | 1.63 |
250.34 | 1.14 | 1.14 |
356.42 | 1.71 | 1.71 |
252.31 | 1.06 | 1.06 |
339.40 | 1.38 | 1.38 |
365.41 | 1.20 | 1.20 |
320.41 | 1.29 | 1.29 |
348.83 | 2.16 | 2.16 |
286.40 | 0.64 | 0.64 |
314.38 | 1.50 | 1.50 |
312.41 | 2.06 | 2.06 |
276.26 | 0.99 | 0.99 |
298.39 | 1.67 | 1.67 |
357.41 | 0.60 | 0.60 |
358.44 | 1.56 | 1.56 |
276.38 | 1.62 | 1.62 |
264.37 | 1.47 | 1.47 |
250.34 | 1.08 | 1.08 |
250.34 | 1.23 | 1.23 |
312.41 | 2.06 | 2.06 |
284.36 | 1.74 | 1.74 |
280.37 | 1.09 | 1.09 |
295.34 | 0.99 | 0.99 |
329.24 | 1.84 | 1.84 |
313.40 | 1.25 | 1.25 |
236.31 | 0.84 | 0.84 |
278.40 | 1.86 | 1.86 |
222.29 | 0.45 | 0.45 |
370.45 | 2.07 | 2.07 |
304.43 | 2.39 | 2.39 |
346.86 | 2.71 | 2.71 |
299.37 | 2.13 | 2.13 |
252.31 | 0.07 | 0.07 |
263.34 | 0.79 | 0.79 |
279.38 | 1.41 | 1.41 |
238.29 | -0.58 | -0.58 |
328.41 | 1.68 | 1.68 |
300.36 | 1.45 | 1.45 |
278.40 | 2.01 | 2.01 |
355.69 | 2.39 | 2.39 |
379.91 | 0.45 | 0.45 |
326.87 | 2.01 | 2.01 |
442.51 | 2.45 | 2.45 |
448.90 | 2.32 | 2.32 |