Basic Information
ID: ALA786468
Type: Functional
Description: Inhibitory activity on AII (100 ng/kg iv)-induced pressor response after administration at 0.1 mg/kg po in conscious male Sprague-Dawley rats at 5 h.
Activity Charts
Bioactivity
Activity Types for Assay ALA786468
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.52 | 4.97 | 4.97 |
| 480.57 | 5.45 | 5.45 |
| 508.63 | 6.23 | 6.23 |
| 466.55 | 5.06 | 5.06 |
| 466.55 | 4.98 | 4.98 |
| 610.67 | 6.32 | 6.32 |
| 440.46 | 4.03 | 4.03 |
| 1133.32 | ||
| 622.73 | 7.26 | 7.26 |
| 570.61 | 5.39 | 5.39 |
| 568.63 | 5.95 | 5.95 |
| 600.64 | 5.70 | 5.70 |
| 564.60 | 5.49 | 5.49 |
| 1353.37 | ||
| 526.55 | 4.40 | 4.40 |
| 574.60 | 5.30 | 5.30 |
| 552.55 | 4.54 | 4.54 |
| 582.62 | 5.54 | 5.54 |
| 598.66 | 6.18 | 6.18 |
| 596.64 | 5.93 | 5.93 |
| 566.62 | 5.18 | 5.18 |
| 554.61 | 5.03 | 5.03 |
| 466.55 | 4.98 | 4.98 |
| 566.66 | 5.98 | 5.98 |
| 556.58 | 5.01 | 5.01 |
| 582.62 | 5.54 | 5.54 |
| 568.59 | 5.01 | 5.01 |
| 556.58 | 5.01 | 5.01 |
| 526.55 | 4.40 | 4.40 |
| 512.53 | 4.01 | 4.01 |
| 523.64 | 4.99 | 4.99 |
| 543.63 | 6.03 | 6.03 |
| 580.65 | 5.57 | 5.57 |
| 540.58 | 4.79 | 4.79 |
| 563.71 | 5.92 | 5.92 |
| 565.68 | 4.76 | 4.76 |
| 540.58 | 4.64 | 4.64 |
| 496.57 | 4.42 | 4.42 |
| 422.92 | 4.27 | 4.27 |