Basic Information
ID: ALA804883
Type: Binding
Description: In vitro inhibitory activity against [3H]DTG binding to Sigma opioid receptor in guinea pig brain membrane homogenates
Organism: Cavia porcellus
Tissue: Brain
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA804883
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 239.32 | 3.76 | 3.76 |
| 243.35 | 2.72 | 2.72 |
| 355.22 | 3.42 | 3.42 |
| 267.38 | 4.27 | 4.27 |
| 351.19 | 3.66 | 3.66 |
| 463.06 | 4.35 | 4.35 |
| 319.45 | 4.90 | 4.90 |
| 284.32 | 3.27 | 3.27 |
| 270.29 | 2.96 | 2.96 |
| 295.43 | 5.39 | 5.39 |
| 295.43 | 5.39 | 5.39 |
| 323.48 | 5.74 | 5.74 |
| 239.32 | 3.76 | 3.76 |
| 239.32 | 3.76 | 3.76 |
| 211.27 | 3.15 | 3.15 |
| 314.39 | 3.29 | 3.29 |
| 267.38 | 4.27 | 4.27 |
| 439.30 | 5.92 | 5.92 |
| 267.38 | 4.27 | 4.27 |
| 269.35 | 2.93 | 2.93 |
| 256.31 | 2.34 | 2.34 |
| 337.43 | 5.97 | 5.97 |
| 327.43 | 5.22 | 5.22 |
| 223.36 | 2.77 | 2.77 |
| 363.46 | 6.48 | 6.48 |
| 271.32 | 3.16 | 3.16 |
| 231.34 | 2.86 | 2.86 |
| 239.36 | 2.58 | 2.58 |
| 347.26 | 5.18 | 5.18 |
| 283.42 | 3.36 | 3.36 |
| 463.06 | 4.35 | 4.35 |
| 311.39 | 5.45 | 5.45 |
| 286.29 | 2.67 | 2.67 |
| 397.11 | 5.29 | 5.29 |
| 295.43 | 5.05 | 5.05 |
| 295.43 | 5.39 | 5.39 |
| 240.31 | 2.64 | 2.64 |
| 171.29 | 1.70 | 1.70 |
| 285.44 | 3.75 | 3.75 |
| 283.42 | 3.50 | 3.50 |
| 237.31 | 2.95 | 2.95 |
| 345.49 | 5.26 | 5.26 |
| 369.06 | 4.67 | 4.67 |
| 209.25 | 2.73 | 2.73 |
| 223.28 | 2.65 | 2.65 |
| 372.04 | 5.55 | 5.55 |
| 242.12 | 0.82 | 0.82 |
| 410.01 | 5.38 | 5.38 |
| 363.98 | 4.04 | 4.04 |
| 290.80 | 2.94 | 2.94 |
| 311.90 | 3.40 | 3.40 |
| 431.75 | 4.05 | 4.05 |
| 554.31 | 9.13 | 9.13 |
| 345.92 | 3.63 | 3.63 |
| 459.80 | 4.77 | 4.77 |
| 484.13 | 6.26 | 6.26 |
| 407.99 | 5.62 | 5.62 |
| 363.98 | 3.75 | 3.75 |
| 283.85 | 2.48 | 2.48 |
| 353.64 | 2.82 | 2.82 |
| 168.04 | -0.64 | -0.64 |
| 433.76 | 4.23 | 4.23 |
| 277.76 | 2.76 | 2.76 |
| 320.23 | 2.50 | 2.50 |
| 431.75 | 4.20 | 4.20 |
| 347.93 | 4.28 | 4.28 |
| 497.94 | 6.46 | 6.46 |
| 365.78 | 3.58 | 3.58 |
| 328.30 | 2.48 | 2.48 |
| 436.04 | 6.33 | 6.33 |
| 407.99 | 5.76 | 5.76 |