Basic Information
ID: ALA806403
Type: Functional
Description: Inhibition of oncogene product p185 erbB-2 from human breast cancer cells(SK-BR-3 cells) at 50 mg/kg dose.
Cell type: SK-BR-3
Activity Charts
Bioactivity
Activity Types for Assay ALA806403
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 560.64 | 2.41 | 2.41 |
| 602.73 | 1.70 | 1.70 |
| 585.70 | 2.54 | 2.54 |
| 639.54 | 3.13 | 3.13 |
| 657.80 | 3.56 | 3.56 |
| 685.82 | 2.01 | 2.01 |
| 667.81 | 2.58 | 2.58 |
| 641.77 | 2.02 | 2.02 |
| 639.75 | 1.80 | 1.80 |
| 653.78 | 2.25 | 2.25 |
| 602.73 | 1.63 | 1.63 |
| 591.70 | 1.57 | 1.57 |
| 605.73 | 1.96 | 1.96 |
| 615.72 | 2.49 | 2.49 |
| 651.76 | 3.64 | 3.64 |
| 617.74 | 1.91 | 1.91 |
| 619.71 | 2.05 | 2.05 |
| 587.71 | 2.76 | 2.76 |
| 547.65 | 1.94 | 1.94 |
| 587.71 | 2.76 | 2.76 |
| 601.70 | 1.44 | 1.44 |
| 643.78 | 3.81 | 3.81 |
| 730.95 | 2.17 | 2.17 |
| 651.77 | 2.02 | 2.02 |
| 587.71 | 2.69 | 2.69 |
| 715.85 | 3.37 | 3.37 |
| 602.69 | 0.84 | 0.84 |
| 654.81 | 2.45 | 2.45 |
| 619.78 | 2.71 | 2.71 |
| 559.66 | 1.98 | 1.98 |
| 585.70 | 2.51 | 2.51 |
| 603.71 | 1.66 | 1.66 |
| 589.69 | 1.34 | 1.34 |
| 545.63 | 1.72 | 1.72 |
| 593.69 | 2.55 | 2.55 |
| 653.78 | 2.64 | 2.64 |
| 585.70 | 2.17 | 2.17 |
| 613.75 | 3.29 | 3.29 |
| 642.79 | 2.35 | 2.35 |
| 605.75 | 2.28 | 2.28 |
| 630.78 | 2.30 | 2.30 |
| 603.71 | 1.73 | 1.73 |
| 583.68 | 1.98 | 1.98 |
| 561.68 | 2.21 | 2.21 |
| 643.73 | 2.31 | 2.31 |
| 653.75 | 1.24 | 1.24 |
| 713.61 | 3.18 | 3.18 |
| 635.76 | 3.55 | 3.55 |
| 615.72 | 1.69 | 1.69 |
| 630.74 | 1.49 | 1.49 |
| 619.71 | 0.70 | 0.70 |
| 621.80 | 2.94 | 2.94 |
| 601.74 | 3.15 | 3.15 |
| 589.73 | 2.98 | 2.98 |
| 587.71 | 2.74 | 2.74 |
| 562.66 | 3.70 | 3.70 |
| 681.79 | 1.65 | 1.65 |
| 693.85 | 3.05 | 3.05 |
| 576.69 | 4.36 | 4.36 |
| 643.73 | 4.40 | 4.40 |
| 562.66 | 3.57 | 3.57 |
| 562.66 | 2.63 | 2.63 |
| 591.68 | 2.32 | 2.32 |
| 619.72 | 4.75 | 4.75 |
| 639.75 | 3.19 | 3.19 |
| 618.73 | 4.95 | 4.95 |
| 628.75 | 3.33 | 3.33 |
| 667.76 | 1.34 | 1.34 |
| 585.70 | 2.47 | 2.47 |
| 617.70 | 1.83 | 1.83 |
| 643.78 | 2.24 | 2.24 |
| 546.62 | 2.32 | 2.32 |
| 603.71 | 1.73 | 1.73 |
| 603.71 | 1.73 | 1.73 |
| 603.71 | 1.73 | 1.73 |
| 603.71 | 1.73 | 1.73 |
| 603.71 | 2.00 | 2.00 |
| 605.73 | 2.22 | 2.22 |
| 589.73 | 2.99 | 2.99 |
| 584.71 | 2.63 | 2.63 |
| 633.74 | 1.97 | 1.97 |