Basic Information
ID: ALA807623
Type: Binding
Description: In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes
Tissue: Brain
Subcellular Fraction: Synaptosomes
Activity Charts
Bioactivity
Activity Types for Assay ALA807623
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 412.02 | 5.04 | 5.04 |
| 371.91 | 4.31 | 4.31 |
| 388.89 | 3.25 | 3.25 |
| 434.36 | 4.77 | 4.77 |
| 436.38 | 4.85 | 4.85 |
| 435.35 | 4.13 | 4.13 |
| 415.96 | 4.51 | 4.51 |
| 493.77 | 4.84 | 4.84 |
| 460.86 | 3.81 | 3.81 |
| 431.96 | 4.21 | 4.21 |
| 428.02 | 4.63 | 4.63 |
| 414.98 | 3.68 | 3.68 |
| 457.06 | 4.50 | 4.50 |
| 421.99 | 4.57 | 4.57 |
| 457.79 | 4.56 | 4.56 |
| 391.90 | 2.59 | 2.59 |
| 457.42 | 4.58 | 4.58 |
| 386.88 | 3.17 | 3.17 |
| 401.93 | 4.20 | 4.20 |
| 444.02 | 5.01 | 5.01 |
| 459.87 | 4.45 | 4.45 |
| 454.78 | 5.12 | 5.12 |
| 456.80 | 5.20 | 5.20 |
| 457.79 | 4.56 | 4.56 |
| 419.92 | 4.34 | 4.34 |
| 437.37 | 4.21 | 4.21 |
| 422.98 | 3.93 | 3.93 |
| 452.93 | 4.29 | 4.29 |
| 437.37 | 4.21 | 4.21 |
| 477.84 | 4.93 | 4.93 |
| 420.91 | 3.70 | 3.70 |
| 417.91 | 4.26 | 4.26 |
| 416.95 | 3.87 | 3.87 |
| 389.88 | 2.65 | 2.65 |
| 438.98 | 3.63 | 3.63 |
| 426.05 | 5.43 | 5.43 |
| 492.78 | 5.47 | 5.47 |
| 388.89 | 3.25 | 3.25 |
| 401.93 | 4.28 | 4.28 |
| 422.35 | 4.54 | 4.54 |
| 419.92 | 4.34 | 4.34 |
| 422.98 | 3.93 | 3.93 |
| 401.93 | 4.20 | 4.20 |
| 429.01 | 3.99 | 3.99 |
| 387.91 | 3.89 | 3.89 |
| 456.80 | 5.20 | 5.20 |
| 459.87 | 4.45 | 4.45 |
| 449.93 | 4.70 | 4.70 |
| 385.94 | 4.70 | 4.70 |
| 429.01 | 3.99 | 3.99 |
| 442.00 | 4.93 | 4.93 |
| 422.98 | 3.93 | 3.93 |
| 459.87 | 4.45 | 4.45 |
| 460.86 | 3.81 | 3.81 |
| 422.98 | 3.93 | 3.93 |
| 422.98 | 3.93 | 3.93 |
| 422.98 | 3.93 | 3.93 |
| 451.94 | 4.78 | 4.78 |
| 416.95 | 3.87 | 3.87 |
| 414.93 | 3.79 | 3.79 |
| 442.99 | 4.30 | 4.30 |
| 421.87 | 4.09 | 4.09 |
| 413.95 | 4.43 | 4.43 |
| 422.98 | 3.93 | 3.93 |
| 402.92 | 3.64 | 3.64 |
| 422.35 | 4.54 | 4.54 |
| 424.88 | 3.53 | 3.53 |