Basic Information
ID: ALA808362
Type: Functional
Description: Effective dose after subcutaneous administration to TPTX rats for 50% reduction of hypercalcemia
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA808362
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 235.07 | -1.66 | -1.66 |
| 249.10 | -1.27 | -1.27 |
| 273.16 | 0.50 | 0.50 |
| 249.10 | -1.27 | -1.27 |
| 367.28 | 0.99 | 0.99 |
| 259.13 | 0.11 | 0.11 |
| 367.28 | 0.94 | 0.94 |
| 353.25 | 0.55 | 0.55 |
| 277.15 | -0.49 | -0.49 |
| 263.12 | -1.06 | -1.06 |
| 324.19 | 1.35 | 1.35 |
| 263.12 | -0.88 | -0.88 |
| 287.19 | 0.94 | 0.94 |
| 288.16 | 0.50 | 0.50 |
| 369.25 | 0.39 | 0.39 |
| 272.09 | -1.05 | -1.05 |
| 381.30 | 1.33 | 1.33 |
| 319.23 | 0.50 | 0.50 |
| 397.30 | 1.09 | 1.09 |
| 339.22 | 0.21 | 0.21 |
| 397.30 | 1.17 | 1.17 |
| 397.30 | 1.17 | 1.17 |
| 395.33 | 1.72 | 1.72 |
| 403.69 | 1.04 | 1.04 |
| 399.34 | 1.49 | 1.49 |
| 369.25 | 0.44 | 0.44 |
| 333.18 | 0.92 | 0.92 |
| 316.21 | 1.32 | 1.32 |
| 411.33 | 1.56 | 1.56 |
| 347.20 | 0.98 | 0.98 |
| 286.12 | -0.66 | -0.66 |
| 286.12 | -0.73 | -0.73 |
| 376.20 | 0.12 | 0.12 |
| 286.12 | -0.74 | -0.74 |
| 271.11 | -0.53 | -0.53 |
| 291.18 | 0.87 | 0.87 |
| 381.30 | 1.25 | 1.25 |
| 286.12 | -0.81 | -0.81 |
| 378.28 | 1.98 | 1.98 |
| 273.08 | -1.72 | -1.72 |
| 272.09 | -1.05 | -1.05 |
| 316.21 | 1.15 | 1.15 |
| 257.08 | -0.54 | -0.54 |
| 273.14 | 0.37 | 0.37 |
| 302.19 | 0.76 | 0.76 |
| 274.13 | 0.19 | 0.19 |
| 417.72 | 1.43 | 1.43 |
| 413.30 | 0.79 | 0.79 |
| 288.16 | 0.50 | 0.50 |
| 385.32 | 1.15 | 1.15 |
| 300.14 | -0.50 | -0.50 |
| 286.12 | -0.74 | -0.74 |
| 330.24 | 1.54 | 1.54 |
| 286.12 | -1.04 | -1.04 |
| 397.30 | 1.17 | 1.17 |
| 409.36 | 2.11 | 2.11 |
| 425.36 | 1.95 | 1.95 |
| 425.36 | 1.95 | 1.95 |
| 353.25 | 0.60 | 0.60 |
| 381.30 | 1.33 | 1.33 |
| 433.79 | 2.15 | 2.15 |
| 401.26 | 0.92 | 0.92 |
| 383.27 | 0.78 | 0.78 |
| 401.72 | 1.60 | 1.60 |
| 385.32 | 1.10 | 1.10 |
| 371.29 | 0.76 | 0.76 |
| 291.18 | -0.28 | -0.28 |
| 291.18 | -0.28 | -0.28 |
| 367.28 | 0.99 | 0.99 |
| 245.11 | -0.28 | -0.28 |
| 219.07 | -0.81 | -0.81 |
| 272.09 | -1.12 | -1.12 |
| 348.19 | 0.62 | 0.62 |
| 397.28 | 1.40 | 1.40 |
| 247.12 | -0.38 | -0.38 |
| 393.31 | 1.65 | 1.65 |
| 379.29 | 1.26 | 1.26 |
| 399.70 | 1.52 | 1.52 |
| 331.24 | 0.64 | 0.64 |
| 303.19 | -0.14 | -0.14 |
| 365.26 | 0.87 | 0.87 |
| 277.15 | -0.67 | -0.67 |
| 249.10 | -1.40 | -1.40 |
| 262.14 | -1.09 | -1.09 |
| 318.20 | -1.37 | -1.37 |
| 331.24 | 0.64 | 0.64 |
| 317.22 | 0.25 | 0.25 |
| 270.19 | 1.64 | 1.64 |
| 350.23 | 1.86 | 1.86 |
| 275.13 | -1.01 | -1.01 |
| 289.16 | -0.53 | -0.53 |
| 333.26 | 0.89 | 0.89 |
| 275.13 | -1.01 | -1.01 |
| 380.27 | 0.20 | 0.20 |
| 421.37 | 2.43 | 2.43 |
| 247.08 | -1.79 | -1.79 |
| 307.14 | 0.61 | 0.61 |
| 275.13 | -0.87 | -0.87 |
| 277.11 | -1.49 | -1.49 |
| 221.04 | -2.05 | -2.05 |
| 303.19 | -0.14 | -0.14 |
| 290.11 | -1.12 | -1.12 |