Basic Information
ID: ALA812446
Type: Binding
Description: Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 uM T(S)2.
Organism: Trypanosoma cruzi
Activity Charts
Bioactivity
Activity Types for Assay ALA812446
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 172.18 | 2.01 | 2.01 |
| 188.18 | 1.72 | 1.72 |
| 288.30 | 2.73 | 2.73 |
| 272.30 | 3.03 | 3.03 |
| 286.33 | 3.42 | 3.42 |
| 302.33 | 3.12 | 3.12 |
| 625.77 | 5.11 | 5.11 |
| 596.77 | 1.14 | 1.14 |
| 386.44 | 4.43 | 4.43 |
| 260.24 | 1.95 | 1.95 |
| 413.52 | 2.01 | 2.01 |
| 383.49 | 1.92 | 1.92 |
| 397.52 | 2.31 | 2.31 |
| 482.58 | 1.18 | 1.18 |
| 356.42 | 2.03 | 2.03 |
| 342.39 | 1.64 | 1.64 |
| 326.40 | 1.94 | 1.94 |
| 274.27 | 2.34 | 2.34 |
| 583.69 | 3.94 | 3.94 |
| 652.79 | 3.97 | 3.97 |
| 597.71 | 4.33 | 4.33 |
| 699.84 | 5.69 | 5.69 |
| 615.68 | 3.35 | 3.35 |
| 684.79 | 3.38 | 3.38 |
| 629.71 | 3.74 | 3.74 |
| 428.49 | 4.34 | 4.34 |
| 540.66 | 3.27 | 3.27 |
| 471.56 | 3.93 | 3.93 |
| 343.43 | 1.96 | 1.96 |
| 566.74 | 3.52 | 3.52 |
| 510.73 | 1.46 | 1.46 |
| 768.95 | 5.72 | 5.72 |
| 713.87 | 6.08 | 6.08 |
| 652.88 | 2.70 | 2.70 |
| 680.93 | 3.48 | 3.48 |
| 358.39 | 3.65 | 3.65 |
| 330.34 | 2.87 | 2.87 |
| 302.28 | 2.09 | 2.09 |
| 624.83 | 1.92 | 1.92 |
| 740.90 | 4.94 | 4.94 |
| 510.64 | 1.96 | 1.96 |
| 685.82 | 5.30 | 5.30 |
| 639.79 | 5.50 | 5.50 |
| 667.85 | 6.28 | 6.28 |
| 399.49 | 1.62 | 1.62 |
| 538.69 | 2.74 | 2.74 |
| 370.50 | 1.29 | 1.29 |
| 258.32 | 1.67 | 1.67 |
| 373.45 | 4.17 | 4.17 |
| 359.42 | 3.78 | 3.78 |
| 542.68 | 3.61 | 3.61 |
| 357.45 | 4.47 | 4.47 |
| 329.40 | 3.69 | 3.69 |
| 736.95 | 6.31 | 6.31 |
| 341.46 | 1.91 | 1.91 |
| 317.39 | 0.96 | 0.96 |
| 388.51 | 1.33 | 1.33 |
| 386.50 | 0.99 | 0.99 |
| 372.51 | 1.63 | 1.63 |
| 343.42 | 4.08 | 4.08 |
| 315.37 | 3.30 | 3.30 |
| 681.87 | 6.67 | 6.67 |
| 327.43 | 2.25 | 2.25 |
| 274.32 | 1.37 | 1.37 |
| 244.25 | 2.25 | 2.25 |
| 671.79 | 4.91 | 4.91 |
| 301.39 | 1.26 | 1.26 |
| 258.27 | 2.64 | 2.64 |
| 712.84 | 4.16 | 4.16 |
| 643.74 | 4.13 | 4.13 |
| 708.90 | 5.53 | 5.53 |
| 653.82 | 5.89 | 5.89 |
| 657.76 | 4.52 | 4.52 |
| 611.74 | 4.72 | 4.72 |
| 345.40 | 3.39 | 3.39 |
| 680.85 | 4.75 | 4.75 |
| 331.37 | 3.00 | 3.00 |