Assay Report Card

Basic Information

ID: ALA812860

Type: Binding

Description: Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissue

Activity Charts

Bioactivity

Activity Types for Assay ALA812860

IC50

Total(163)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
538.76	4.14	4.14
596.76	2.22	2.22
638.84	2.32	2.32
542.79	4.88	4.88
517.74	2.71	2.71
444.64	3.63	3.63
566.79	1.61	1.61
512.72	3.24	3.24
578.86	6.21	6.21
486.68	3.46	3.46
456.61	3.68	3.68
514.69	2.29	2.29
501.69	2.51	2.51
513.66	2.49	2.49
541.76	4.46	4.46
499.63	2.57	2.57
542.75	2.17	2.17
515.72	2.76	2.76
499.68	3.39	3.39
638.84	2.32	2.32
549.74	4.15	4.15
471.67	3.52	3.52
554.72	2.20	2.20
563.76	4.08	4.08
548.79	5.63	5.63
499.68	3.43	3.43
541.71	2.89	2.89
601.81	1.71	1.71
552.76	1.22	1.22
542.70	3.34	3.34
565.74	3.37	3.37
520.74	4.85	4.85
534.77	5.24	5.24
687.93	2.50	2.50
673.90	2.49	2.49
538.76	4.52	4.52
520.74	4.85	4.85
414.57	4.03	4.03
399.56	3.77	3.77
548.75	4.75	4.75
552.74	3.41	3.41
517.69	2.96	2.96
549.74	4.15	4.15
549.74	4.15	4.15
506.71	4.92	4.92
565.74	3.68	3.68
565.74	3.38	3.38
508.75	3.82	3.82
484.71	4.50	4.50
595.85	4.17	4.17
576.76	4.05	4.05
589.60	4.34	4.34
538.76	4.31	4.31
609.75	2.41	2.41
652.86	2.33	2.33
652.86	2.33	2.33
485.65	3.04	3.04
530.74	2.20	2.20
530.74	2.20	2.20
556.73	3.73	3.73
593.79	4.04	4.04
530.73	3.95	3.95
484.66	3.64	3.64
514.69	2.37	2.37
532.71	2.60	2.60
512.76	5.19	5.19
507.70	4.32	4.32
507.70	4.32	4.32
567.72	2.47	2.47
444.64	3.63	3.63
524.73	3.58	3.58
416.59	3.95	3.95
401.57	3.56	3.56
402.60	3.45	3.45
611.81	3.94	3.94
521.73	4.25	4.25
445.63	3.16	3.16
638.84	2.32	2.32
502.68	3.47	3.47
485.69	3.05	3.05
524.69	3.28	3.28
543.69	2.84	2.84
540.69	2.06	2.06
500.71	3.48	3.48
544.76	2.29	2.29
556.73	2.68	2.68
608.77	3.12	3.12
512.67	3.08	3.08
524.73	3.58	3.58
626.84	3.67	3.67
593.81	1.81	1.81
558.75	1.64	1.64
543.77	3.42	3.42
529.75	3.03	3.03
616.85	3.55	3.55
645.89	3.51	3.51
630.88	3.34	3.34
473.68	2.96	2.96
510.70	3.57	3.57
610.74	1.95	1.95
592.78	2.09	2.09
539.75	3.76	3.76
567.80	3.39	3.39
555.79	4.57	4.57
510.70	3.95	3.95
549.74	3.69	3.69
459.61	3.41	3.41
549.74	3.69	3.69
549.74	3.69	3.69
510.70	3.50	3.50
510.70	3.57	3.57
510.70	3.57	3.57
501.74	3.59	3.59
637.85	3.16	3.16
515.76	3.98	3.98
610.82	3.86	3.86
524.73	3.89	3.89
524.73	3.96	3.96
401.57	3.56	3.56
538.71	3.02	3.02
539.79	3.95	3.95
554.80	3.88	3.88
622.85	1.49	1.49
541.76	3.05	3.05
522.72	4.04	4.04
535.71	3.76	3.76
535.71	3.76	3.76
567.80	3.50	3.50
539.75	2.90	2.90
402.60	3.45	3.45
440.61	3.85	3.85
512.68	2.29	2.29
535.71	3.76	3.76
701.91	1.94	1.94
514.69	3.57	3.57
510.70	3.57	3.57
512.68	2.36	2.36
591.80	2.85	2.85
512.74	4.98	4.98
499.72	3.31	3.31
606.87	5.66	5.66
430.61	2.89	2.89
541.80	4.39	4.39
621.91	3.75	3.75
542.77	3.89	3.89
535.75	4.64	4.64
527.78	4.00	4.00
577.81	2.38	2.38
549.80	2.70	2.70
593.86	2.97	2.97
521.73	4.25	4.25
521.73	4.25	4.25
538.71	3.89	3.89
472.65	3.07	3.07
430.61	2.89	2.89
543.69	2.89	2.89
565.80	2.37	2.37
581.80	1.34	1.34
565.80	2.37	2.37