Basic Information
ID: ALA814228
Type: Binding
Description: Ratio of IC50 to that of 10x compound against Steroid 5-alpha-reductase
Activity Charts
Bioactivity
Activity Types for Assay ALA814228
IC50 ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.55 | 3.81 | 3.81 |
| 303.45 | 2.99 | 2.99 |
| 371.52 | 4.46 | 4.46 |
| 344.50 | 3.34 | 3.34 |
| 386.58 | 4.46 | 4.46 |
| 400.61 | 4.89 | 4.89 |
| 414.63 | 5.24 | 5.24 |
| 412.62 | 5.01 | 5.01 |
| 289.42 | 2.64 | 2.64 |
| 331.46 | 3.07 | 3.07 |
| 316.44 | 2.39 | 2.39 |
| 372.55 | 3.77 | 3.77 |
| 386.58 | 4.11 | 4.11 |
| 344.50 | 3.04 | 3.04 |
| 358.53 | 3.38 | 3.38 |
| 330.47 | 3.69 | 3.69 |
| 347.54 | 4.09 | 4.09 |
| 333.52 | 3.85 | 3.85 |
| 349.51 | 2.96 | 2.96 |
| 444.70 | 5.75 | 5.75 |
| 416.65 | 4.97 | 4.97 |
| 411.56 | 4.97 | 4.97 |
| 383.51 | 4.19 | 4.19 |
| 416.65 | 5.11 | 5.11 |
| 416.65 | 5.11 | 5.11 |
| 402.62 | 4.58 | 4.58 |
| 402.62 | 4.58 | 4.58 |
| 400.61 | 4.19 | 4.19 |
| 402.58 | 3.32 | 3.32 |
| 406.59 | 4.28 | 4.28 |
| 418.62 | 3.96 | 3.96 |
| 448.65 | 3.93 | 3.93 |
| 375.55 | 4.42 | 4.42 |
| 388.60 | 4.33 | 4.33 |
| 305.46 | 3.21 | 3.21 |
| 355.45 | 3.55 | 3.55 |
| 402.62 | 4.72 | 4.72 |
| 316.44 | 4.22 | 4.22 |
| 418.62 | 3.96 | 3.96 |
| 318.46 | 2.61 | 2.61 |
| 375.55 | 4.28 | 4.28 |
| 405.65 | 5.52 | 5.52 |
| 359.55 | 4.74 | 4.74 |
| 413.61 | 4.08 | 4.08 |
| 330.47 | 4.31 | 4.31 |
| 414.63 | 4.89 | 4.89 |
| 357.54 | 4.77 | 4.77 |
| 357.54 | 4.77 | 4.77 |
| 345.53 | 4.30 | 4.30 |
| 381.49 | 4.31 | 4.31 |
| 357.50 | 3.34 | 3.34 |
| 389.58 | 4.81 | 4.81 |
| 343.51 | 4.18 | 4.18 |
| 584.97 | 9.84 | 9.84 |
| 359.51 | 3.71 | 3.71 |
| 376.54 | 2.57 | 2.57 |
| 444.70 | 5.80 | 5.80 |
| 430.68 | 5.45 | 5.45 |
| 373.54 | 4.05 | 4.05 |
| 424.61 | 4.96 | 4.96 |
| 410.58 | 4.61 | 4.61 |
| 331.50 | 4.01 | 4.01 |
| 417.59 | 3.37 | 3.37 |
| 396.58 | 4.90 | 4.90 |
| 445.65 | 3.45 | 3.45 |
| 404.60 | 3.35 | 3.35 |
| 444.70 | 5.94 | 5.94 |
| 402.62 | 4.72 | 4.72 |
| 388.60 | 4.38 | 4.38 |
| 402.62 | 4.72 | 4.72 |
| 388.60 | 4.38 | 4.38 |
| 374.57 | 3.99 | 3.99 |
| 360.54 | 3.60 | 3.60 |
| 346.51 | 3.21 | 3.21 |
| 347.54 | 4.09 | 4.09 |
| 359.51 | 3.93 | 3.93 |
| 404.60 | 3.31 | 3.31 |
| 347.50 | 3.64 | 3.64 |
| 333.47 | 3.30 | 3.30 |
| 430.68 | 5.60 | 5.60 |
| 402.62 | 4.77 | 4.77 |
| 384.52 | 4.58 | 4.58 |
| 353.51 | 4.96 | 4.96 |
| 375.55 | 4.47 | 4.47 |
| 319.49 | 3.50 | 3.50 |
| 371.57 | 5.00 | 5.00 |
| 369.48 | 3.84 | 3.84 |
| 442.69 | 5.72 | 5.72 |
| 331.50 | 4.06 | 4.06 |
| 416.61 | 4.25 | 4.25 |
| 402.62 | 4.72 | 4.72 |
| 346.51 | 3.35 | 3.35 |
| 345.48 | 3.42 | 3.42 |
| 329.48 | 3.83 | 3.83 |
| 373.58 | 5.08 | 5.08 |
| 359.55 | 4.74 | 4.74 |
| 556.92 | 9.02 | 9.02 |
| 402.62 | 4.77 | 4.77 |
| 314.47 | 3.99 | 3.99 |
| 342.53 | 4.63 | 4.63 |
| 368.52 | 4.33 | 4.33 |
| 373.58 | 5.08 | 5.08 |
| 402.58 | 3.32 | 3.32 |
| 382.55 | 4.68 | 4.68 |
| 380.53 | 4.45 | 4.45 |
| 366.51 | 4.11 | 4.11 |
| 371.57 | 4.86 | 4.86 |
| 357.54 | 4.52 | 4.52 |
| 411.59 | 4.00 | 4.00 |
| 381.49 | 3.96 | 3.96 |
| 348.49 | 2.23 | 2.23 |
| 371.57 | 4.86 | 4.86 |
| 357.54 | 4.52 | 4.52 |
| 367.47 | 3.62 | 3.62 |
| 400.61 | 4.55 | 4.55 |
| 414.63 | 4.89 | 4.89 |
| 386.58 | 4.16 | 4.16 |
| 442.69 | 5.57 | 5.57 |
| 428.66 | 5.23 | 5.23 |
| 386.58 | 4.67 | 4.67 |
| 358.53 | 3.89 | 3.89 |
| 330.47 | 2.73 | 2.73 |
| 404.60 | 4.55 | 4.55 |
| 420.59 | 3.20 | 3.20 |
| 374.57 | 4.04 | 4.04 |
| 403.61 | 4.13 | 4.13 |
| 388.60 | 4.38 | 4.38 |
| 329.48 | 4.13 | 4.13 |
| 374.57 | 3.99 | 3.99 |
| 400.61 | 4.64 | 4.64 |
| 331.50 | 4.06 | 4.06 |
| 346.51 | 3.35 | 3.35 |
| 345.53 | 4.40 | 4.40 |