Basic Information
ID: ALA815663
Type: Binding
Description: In vitro inhibition of partially purified L1210 thymidylate synthase (TS).
Format: BAO_0000357
Target: Thymidylate synthase(ALA3160)
Document: ALA1125690
In vitro inhibition of partially purified L1210 thymidylate synthase (TS).: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA815663
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.51 | 1.15 | 1.15 |
| 491.50 | 2.12 | 2.12 |
| 485.52 | 2.34 | 2.34 |
| 458.50 | 2.39 | 2.39 |
| 508.50 | 2.89 | 2.89 |
| 473.51 | 2.17 | 2.17 |
| 459.48 | 1.78 | 1.78 |
| 445.46 | 1.76 | 1.76 |
| 466.49 | 2.31 | 2.31 |
| 482.52 | 2.39 | 2.39 |
| 488.52 | 1.75 | 1.75 |
| 491.50 | 2.34 | 2.34 |
| 444.47 | 2.37 | 2.37 |
| 502.55 | 2.14 | 2.14 |
| 486.55 | 3.17 | 3.17 |
| 490.51 | 2.73 | 2.73 |
| 475.48 | 0.97 | 0.97 |
| 488.52 | 1.96 | 1.96 |
| 479.49 | 1.87 | 1.87 |
| 452.47 | 1.92 | 1.92 |
| 476.49 | 1.92 | 1.92 |
| 483.51 | 1.79 | 1.79 |
| 474.50 | 1.57 | 1.57 |
| 467.48 | 1.70 | 1.70 |
| 483.51 | 2.28 | 2.28 |
| 490.51 | 2.94 | 2.94 |
| 476.49 | 2.55 | 2.55 |
| 503.54 | 1.54 | 1.54 |
| 473.51 | 2.17 | 2.17 |
| 474.50 | 1.57 | 1.57 |
| 454.44 | 0.71 | 0.71 |
| 453.46 | 1.31 | 1.31 |
| 477.48 | 1.31 | 1.31 |
| 472.52 | 2.78 | 2.78 |
| 484.53 | 2.95 | 2.95 |
| 485.47 | 1.65 | 1.65 |
| 475.44 | 1.31 | 1.31 |