Assay Report Card

Basic Information

ID: ALA817099

Type: Binding

Description: Inhibition of radioligand [3H]-AVP binding to the vasopressin V2 receptor in rat kidney tissue

Tissue: Kidney

Activity Charts

Bioactivity

Activity Types for Assay ALA817099

IC50

Total(163)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
538.76	4.14	4.14
596.76	2.22	2.22
638.84	2.32	2.32
542.79	4.88	4.88
517.74	2.71	2.71
444.64	3.63	3.63
566.79	1.61	1.61
512.72	3.24	3.24
578.86	6.21	6.21
486.68	3.46	3.46
456.61	3.68	3.68
514.69	2.29	2.29
501.69	2.51	2.51
513.66	2.49	2.49
541.76	4.46	4.46
499.63	2.57	2.57
542.75	2.17	2.17
515.72	2.76	2.76
499.68	3.39	3.39
638.84	2.32	2.32
549.74	4.15	4.15
471.67	3.52	3.52
554.72	2.20	2.20
563.76	4.08	4.08
548.79	5.63	5.63
499.68	3.43	3.43
541.71	2.89	2.89
601.81	1.71	1.71
552.76	1.22	1.22
542.70	3.34	3.34
565.74	3.37	3.37
520.74	4.85	4.85
534.77	5.24	5.24
687.93	2.50	2.50
673.90	2.49	2.49
538.76	4.52	4.52
520.74	4.85	4.85
414.57	4.03	4.03
399.56	3.77	3.77
548.75	4.75	4.75
552.74	3.41	3.41
517.69	2.96	2.96
549.74	4.15	4.15
549.74	4.15	4.15
506.71	4.92	4.92
565.74	3.68	3.68
565.74	3.38	3.38
508.75	3.82	3.82
484.71	4.50	4.50
595.85	4.17	4.17
576.76	4.05	4.05
589.60	4.34	4.34
538.76	4.31	4.31
609.75	2.41	2.41
652.86	2.33	2.33
652.86	2.33	2.33
485.65	3.04	3.04
530.74	2.20	2.20
530.74	2.20	2.20
556.73	3.73	3.73
593.79	4.04	4.04
530.73	3.95	3.95
484.66	3.64	3.64
514.69	2.37	2.37
532.71	2.60	2.60
512.76	5.19	5.19
507.70	4.32	4.32
507.70	4.32	4.32
567.72	2.47	2.47
444.64	3.63	3.63
524.73	3.58	3.58
416.59	3.95	3.95
401.57	3.56	3.56
402.60	3.45	3.45
611.81	3.94	3.94
521.73	4.25	4.25
445.63	3.16	3.16
638.84	2.32	2.32
502.68	3.47	3.47
485.69	3.05	3.05
524.69	3.28	3.28
543.69	2.84	2.84
540.69	2.06	2.06
500.71	3.48	3.48
544.76	2.29	2.29
556.73	2.68	2.68
608.77	3.12	3.12
512.67	3.08	3.08
524.73	3.58	3.58
626.84	3.67	3.67
593.81	1.81	1.81
558.75	1.64	1.64
543.77	3.42	3.42
529.75	3.03	3.03
616.85	3.55	3.55
645.89	3.51	3.51
630.88	3.34	3.34
473.68	2.96	2.96
510.70	3.57	3.57
610.74	1.95	1.95
592.78	2.09	2.09
539.75	3.76	3.76
567.80	3.39	3.39
555.79	4.57	4.57
510.70	3.95	3.95
549.74	3.69	3.69
459.61	3.41	3.41
549.74	3.69	3.69
549.74	3.69	3.69
510.70	3.50	3.50
510.70	3.57	3.57
510.70	3.57	3.57
501.74	3.59	3.59
637.85	3.16	3.16
515.76	3.98	3.98
610.82	3.86	3.86
524.73	3.89	3.89
524.73	3.96	3.96
401.57	3.56	3.56
538.71	3.02	3.02
539.79	3.95	3.95
554.80	3.88	3.88
622.85	1.49	1.49
541.76	3.05	3.05
522.72	4.04	4.04
535.71	3.76	3.76
535.71	3.76	3.76
567.80	3.50	3.50
539.75	2.90	2.90
402.60	3.45	3.45
440.61	3.85	3.85
512.68	2.29	2.29
535.71	3.76	3.76
701.91	1.94	1.94
514.69	3.57	3.57
510.70	3.57	3.57
512.68	2.36	2.36
591.80	2.85	2.85
512.74	4.98	4.98
499.72	3.31	3.31
606.87	5.66	5.66
430.61	2.89	2.89
541.80	4.39	4.39
621.91	3.75	3.75
542.77	3.89	3.89
535.75	4.64	4.64
527.78	4.00	4.00
577.81	2.38	2.38
549.80	2.70	2.70
593.86	2.97	2.97
521.73	4.25	4.25
521.73	4.25	4.25
538.71	3.89	3.89
472.65	3.07	3.07
430.61	2.89	2.89
543.69	2.89	2.89
565.80	2.37	2.37
581.80	1.34	1.34
565.80	2.37	2.37