Inhibition of radioligand [3H]-AVP binding to the vasopressin V2 receptor in rat kidney tissue

Basic Information

ID: ALA817099

Type: Binding

Description: Inhibition of radioligand [3H]-AVP binding to the vasopressin V2 receptor in rat kidney tissue

Format: BAO_0000019

Tissue: Kidney

Target: Vasopressin V2 receptor(ALA3766)

Document: ALA1126550

Inhibition of radioligand [3H]-AVP binding to the vasopressin V2 receptor in rat kidney tissue: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA817099

IC50

Total(163)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
538.76	4.14	4.14
596.76	2.22	2.22
638.84	2.32	2.32
542.79	4.88	4.88
517.74	2.71	2.71
444.64	3.63	3.63
566.79	1.61	1.61
512.72	3.24	3.24
578.86	6.21	6.21
486.68	3.46	3.46
456.61	3.68	3.68
514.69	2.29	2.29
501.69	2.51	2.51
513.66	2.49	2.49
541.76	4.46	4.46
499.63	2.57	2.57
542.75	2.17	2.17
515.72	2.76	2.76
499.68	3.39	3.39
638.84	2.32	2.32
549.74	4.15	4.15
471.67	3.52	3.52
554.72	2.20	2.20
563.76	4.08	4.08
548.79	5.63	5.63
499.68	3.43	3.43
541.71	2.89	2.89
601.81	1.71	1.71
552.76	1.22	1.22
542.70	3.34	3.34
565.74	3.37	3.37
520.74	4.85	4.85
534.77	5.24	5.24
687.93	2.50	2.50
673.90	2.49	2.49
538.76	4.52	4.52
520.74	4.85	4.85
414.57	4.03	4.03
399.56	3.77	3.77
548.75	4.75	4.75
552.74	3.41	3.41
517.69	2.96	2.96
549.74	4.15	4.15
549.74	4.15	4.15
506.71	4.92	4.92
565.74	3.68	3.68
565.74	3.38	3.38
508.75	3.82	3.82
484.71	4.50	4.50
595.85	4.17	4.17
576.76	4.05	4.05
589.60	4.34	4.34
538.76	4.31	4.31
609.75	2.41	2.41
652.86	2.33	2.33
652.86	2.33	2.33
485.65	3.04	3.04
530.74	2.20	2.20
530.74	2.20	2.20
556.73	3.73	3.73
593.79	4.04	4.04
530.73	3.95	3.95
484.66	3.64	3.64
514.69	2.37	2.37
532.71	2.60	2.60
512.76	5.19	5.19
507.70	4.32	4.32
507.70	4.32	4.32
567.72	2.47	2.47
444.64	3.63	3.63
524.73	3.58	3.58
416.59	3.95	3.95
401.57	3.56	3.56
402.60	3.45	3.45
611.81	3.94	3.94
521.73	4.25	4.25
445.63	3.16	3.16
638.84	2.32	2.32
502.68	3.47	3.47
485.69	3.05	3.05
524.69	3.28	3.28
543.69	2.84	2.84
540.69	2.06	2.06
500.71	3.48	3.48
544.76	2.29	2.29
556.73	2.68	2.68
608.77	3.12	3.12
512.67	3.08	3.08
524.73	3.58	3.58
626.84	3.67	3.67
593.81	1.81	1.81
558.75	1.64	1.64
543.77	3.42	3.42
529.75	3.03	3.03
616.85	3.55	3.55
645.89	3.51	3.51
630.88	3.34	3.34
473.68	2.96	2.96
510.70	3.57	3.57
610.74	1.95	1.95
592.78	2.09	2.09
539.75	3.76	3.76
567.80	3.39	3.39
555.79	4.57	4.57
510.70	3.95	3.95
549.74	3.69	3.69
459.61	3.41	3.41
549.74	3.69	3.69
549.74	3.69	3.69
510.70	3.50	3.50
510.70	3.57	3.57
510.70	3.57	3.57
501.74	3.59	3.59
637.85	3.16	3.16
515.76	3.98	3.98
610.82	3.86	3.86
524.73	3.89	3.89
524.73	3.96	3.96
401.57	3.56	3.56
538.71	3.02	3.02
539.79	3.95	3.95
554.80	3.88	3.88
622.85	1.49	1.49
541.76	3.05	3.05
522.72	4.04	4.04
535.71	3.76	3.76
535.71	3.76	3.76
567.80	3.50	3.50
539.75	2.90	2.90
402.60	3.45	3.45
440.61	3.85	3.85
512.68	2.29	2.29
535.71	3.76	3.76
701.91	1.94	1.94
514.69	3.57	3.57
510.70	3.57	3.57
512.68	2.36	2.36
591.80	2.85	2.85
512.74	4.98	4.98
499.72	3.31	3.31
606.87	5.66	5.66
430.61	2.89	2.89
541.80	4.39	4.39
621.91	3.75	3.75
542.77	3.89	3.89
535.75	4.64	4.64
527.78	4.00	4.00
577.81	2.38	2.38
549.80	2.70	2.70
593.86	2.97	2.97
521.73	4.25	4.25
521.73	4.25	4.25
538.71	3.89	3.89
472.65	3.07	3.07
430.61	2.89	2.89
543.69	2.89	2.89
565.80	2.37	2.37
581.80	1.34	1.34
565.80	2.37	2.37