Basic Information
ID: ALA817769
Type: Binding
Description: Inhibition of tubulin polymerization interacting at the colchicine binding site.
Activity Charts
Bioactivity
Activity Types for Assay ALA817769
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 271.30 | 3.40 | 3.40 |
| 399.44 | 2.87 | 2.87 |
| 295.29 | 3.34 | 3.34 |
| 251.28 | 3.62 | 3.62 |
| 297.31 | 3.16 | 3.16 |
| 252.27 | 3.01 | 3.01 |
| 320.39 | 4.22 | 4.22 |
| 297.31 | 3.16 | 3.16 |
| 415.51 | 3.58 | 3.58 |
| 401.48 | 3.28 | 3.28 |
| 401.48 | 3.28 | 3.28 |
| 512.03 | 5.53 | 5.53 |
| 522.58 | 4.79 | 4.79 |
| 488.61 | 5.11 | 5.11 |
| 553.68 | 5.26 | 5.26 |
| 508.60 | 5.15 | 5.15 |
| 502.59 | 4.75 | 4.75 |
| 481.59 | 5.38 | 5.38 |
| 388.49 | 4.65 | 4.65 |
| 312.37 | 3.96 | 3.96 |
| 312.37 | 3.96 | 3.96 |
| 388.49 | 4.65 | 4.65 |
| 554.66 | 5.11 | 5.11 |
| 373.47 | 3.41 | 3.41 |
| 429.49 | 3.02 | 3.02 |
| 553.68 | 4.69 | 4.69 |
| 276.75 | 4.03 | 4.03 |
| 321.20 | 4.13 | 4.13 |
| 256.33 | 3.68 | 3.68 |
| 416.54 | 5.43 | 5.43 |
| 344.43 | 4.16 | 4.16 |
| 270.72 | 3.96 | 3.96 |
| 283.26 | 3.48 | 3.48 |
| 314.38 | 3.88 | 3.88 |
| 250.30 | 3.62 | 3.62 |
| 503.58 | 4.83 | 4.83 |
| 496.56 | 5.10 | 5.10 |
| 281.27 | 3.04 | 3.04 |
| 415.51 | 3.58 | 3.58 |
| 256.33 | 3.68 | 3.68 |
| 274.68 | 3.79 | 3.79 |
| 266.30 | 3.32 | 3.32 |
| 264.33 | 3.93 | 3.93 |
| 250.30 | 3.62 | 3.62 |
| 268.29 | 3.76 | 3.76 |
| 266.30 | 3.32 | 3.32 |
| 256.74 | 4.31 | 4.31 |
| 250.30 | 3.62 | 3.62 |
| 450.56 | 5.95 | 5.95 |
| 451.54 | 5.34 | 5.34 |
| 250.30 | 3.62 | 3.62 |
| 242.30 | 3.37 | 3.37 |
| 416.54 | 5.43 | 5.43 |
| 270.36 | 3.99 | 3.99 |
| 256.33 | 3.68 | 3.68 |
| 256.33 | 3.68 | 3.68 |
| 284.75 | 4.27 | 4.27 |
| 308.36 | 3.93 | 3.93 |
| 252.32 | 3.66 | 3.66 |
| 236.32 | 3.96 | 3.96 |
| 270.72 | 3.96 | 3.96 |
| 294.35 | 3.68 | 3.68 |
| 294.31 | 3.38 | 3.38 |
| 333.26 | 4.35 | 4.35 |
| 266.30 | 3.32 | 3.32 |
| 272.31 | 4.16 | 4.16 |
| 306.75 | 4.81 | 4.81 |
| 254.26 | 3.45 | 3.45 |
| 242.30 | 3.37 | 3.37 |
| 286.33 | 4.46 | 4.46 |
| 331.17 | 3.77 | 3.77 |
| 270.72 | 3.55 | 3.55 |
| 286.33 | 4.46 | 4.46 |
| 286.33 | 4.46 | 4.46 |
| 236.27 | 3.31 | 3.31 |
| 272.31 | 4.16 | 4.16 |
| 479.55 | 4.70 | 4.70 |
| 266.30 | 2.91 | 2.91 |
| 300.36 | 4.77 | 4.77 |
| 286.33 | 4.46 | 4.46 |
| 496.56 | 5.10 | 5.10 |
| 286.72 | 3.66 | 3.66 |
| 443.52 | 3.24 | 3.24 |
| 457.55 | 3.54 | 3.54 |
| 270.72 | 3.96 | 3.96 |
| 479.55 | 4.70 | 4.70 |
| 270.72 | 3.96 | 3.96 |
| 443.52 | 3.24 | 3.24 |
| 280.33 | 3.63 | 3.63 |
| 451.54 | 5.34 | 5.34 |
| 250.30 | 3.62 | 3.62 |
| 256.69 | 3.66 | 3.66 |
| 266.30 | 3.32 | 3.32 |
| 286.33 | 4.46 | 4.46 |
| 254.26 | 3.04 | 3.04 |
| 299.71 | 3.99 | 3.99 |
| 286.33 | 4.46 | 4.46 |
| 336.39 | 3.45 | 3.45 |
| 399.44 | 3.29 | 3.29 |
| 496.56 | 5.10 | 5.10 |
| 371.43 | 3.51 | 3.51 |
| 280.28 | 2.92 | 2.92 |
| 385.38 | 4.56 | 4.56 |