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Assay
ALA820592

Assay Report Card

Basic Information

ID: ALA820592

Type: Binding

Description: Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.

Tissue: Blood

Activity Charts

Bioactivity

Activity Types for Assay ALA820592

IC50

Total(71)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
315.41	0.82	0.82
331.41	-0.21	-0.21
383.53	2.24	2.24
389.50	1.82	1.82
423.52	2.26	2.26
471.62	3.04	3.04
485.59	1.78	1.78
499.63	0.36	0.36
434.54	1.23	1.23
485.59	1.78	1.78
435.53	0.62	0.62
484.62	1.12	1.12
563.72	2.45	2.45
611.77	3.24	3.24
514.60	0.48	0.48
471.58	0.17	0.17
520.65	1.93	1.93
472.59	2.56	2.56
549.49	1.54	1.54
502.61	1.87	1.87
538.63	0.43	0.43
535.67	1.67	1.67
521.64	1.33	1.33
521.64	1.33	1.33
595.70	2.92	2.92
525.63	0.27	0.27
520.65	1.93	1.93
521.64	1.33	1.33
471.60	2.14	2.14
502.61	1.87	1.87
470.61	2.74	2.74
418.60	1.14	1.14
420.55	1.59	1.59
471.60	2.14	2.14
384.52	0.90	0.90
476.62	0.84	0.84
423.58	2.59	2.59
460.56	-0.50	-0.50
483.63	2.61	2.61
492.47	3.90	3.90
423.58	2.59	2.59
501.67	2.00	2.00
448.59	2.46	2.46
506.67	2.50	2.50
361.51	1.16	1.16
582.50	2.74	2.74
400.52	0.13	0.13
539.48	2.08	2.08
408.52	-0.65	-0.65
470.59	0.78	0.78
506.67	2.98	2.98
553.68	0.69	0.69
538.63	0.43	0.43
503.60	1.97	1.97
345.44	0.45	0.45
496.63	1.39	1.39
372.47	-0.06	-0.06
484.60	2.38	2.38
527.64	0.74	0.74
375.54	1.55	1.55
489.57	2.12	2.12
495.60	0.65	0.65
473.57	1.96	1.96
596.84	4.15	4.15
490.67	3.39	3.39
488.65	3.28	3.28
476.01	3.38	3.38
523.03	1.57	1.57
609.72	2.60	2.60
471.60	3.17	3.17
471.60	3.17	3.17