Basic Information
ID: ALA820617
Type: Binding
Description: Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells
Format: BAO_0000219
Cell type: L1210
Target: Thymidylate synthase(ALA3160)
Document: ALA1132642
Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA820617
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 476.49 | 1.92 | 1.92 |
| 585.61 | 1.77 | 1.77 |
| 609.64 | 2.33 | 2.33 |
| 706.71 | 3.50 | 3.50 |
| 536.56 | 3.56 | 3.56 |
| 522.53 | 3.17 | 3.17 |
| 550.58 | 2.22 | 2.22 |
| 661.71 | 3.51 | 3.51 |
| 639.58 | 2.66 | 2.66 |
| 549.59 | 2.82 | 2.82 |
| 675.74 | 3.90 | 3.90 |
| 594.63 | 2.02 | 2.02 |
| 592.66 | 3.39 | 3.39 |
| 593.64 | 3.31 | 3.31 |
| 578.63 | 3.00 | 3.00 |
| 580.60 | 1.63 | 1.63 |
| 564.60 | 2.61 | 2.61 |
| 625.64 | 1.99 | 1.99 |
| 661.71 | 3.45 | 3.45 |
| 599.64 | 2.16 | 2.16 |
| 557.60 | 1.98 | 1.98 |
| 566.58 | 1.24 | 1.24 |
| 565.59 | 1.84 | 1.84 |
| 661.71 | 3.59 | 3.59 |
| 599.64 | 2.16 | 2.16 |
| 647.69 | 3.06 | 3.06 |
| 585.61 | 1.77 | 1.77 |
| 627.69 | 2.94 | 2.94 |
| 613.67 | 2.55 | 2.55 |
| 546.56 | 2.45 | 2.45 |
| 532.54 | 2.06 | 2.06 |
| 532.54 | 2.06 | 2.06 |
| 608.66 | 2.41 | 2.41 |
| 550.59 | 3.95 | 3.95 |
| 508.51 | 2.78 | 2.78 |
| 599.64 | 2.16 | 2.16 |
| 477.48 | 1.19 | 1.19 |
| 458.50 | 1.98 | 1.98 |