Basic Information
ID: ALA823551
Type: Binding
Description: Alpha4-beta7 integrin binding affinity was determined in duplicate by a radioligand binding assay using [125I]-VCAM-Ig and a suspension of RPMI-8866 cells (a human B cell line alpha-4-beta-1-beta-7+)
Cell type: B
Activity Charts
Bioactivity
Activity Types for Assay ALA823551
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 591.47 | 4.18 | 4.18 |
| 569.43 | 2.05 | 2.05 |
| 577.49 | 4.54 | 4.54 |
| 614.50 | 3.18 | 3.18 |
| 634.54 | 4.98 | 4.98 |
| 628.58 | 4.97 | 4.97 |
| 580.45 | 3.51 | 3.51 |
| 515.59 | 2.25 | 2.25 |
| 601.51 | 3.68 | 3.68 |
| 453.52 | 0.82 | 0.82 |
| 583.49 | 4.05 | 4.05 |
| 600.52 | 4.19 | 4.19 |
| 598.50 | 3.94 | 3.94 |
| 545.44 | 2.98 | 2.98 |
| 543.43 | 2.93 | 2.93 |
| 526.40 | 2.86 | 2.86 |
| 584.48 | 3.55 | 3.55 |