Basic Information
ID: ALA827846
Type: Binding
Description: Inhibitory concentration against aggrecanase from porcine chondrocytes using [35S]-sulfate (5 mCi/ml) as radioligand and adding IL-1alpha (5 ng/ml) incubated for 10h
Organism: Sus scrofa
Activity Charts
Bioactivity
Activity Types for Assay ALA827846
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 480.56 | 2.98 | 2.98 |
| 452.50 | 2.20 | 2.20 |
| 452.50 | 2.20 | 2.20 |
| 438.48 | 1.81 | 1.81 |
| 438.48 | 1.81 | 1.81 |
| 438.48 | 1.81 | 1.81 |
| 454.93 | 2.33 | 2.33 |
| 438.48 | 1.81 | 1.81 |
| 454.93 | 2.33 | 2.33 |
| 434.51 | 1.98 | 1.98 |
| 452.50 | 2.12 | 2.12 |
| 452.50 | 2.12 | 2.12 |
| 452.50 | 2.12 | 2.12 |
| 472.92 | 2.47 | 2.47 |
| 472.92 | 2.47 | 2.47 |
| 471.54 | 2.22 | 2.22 |
| 471.54 | 2.22 | 2.22 |
| 455.92 | 1.72 | 1.72 |
| 435.50 | 1.38 | 1.38 |